Evidence map›Paper›PMID 32565724›Full record

ArticleMediators of inflammation2020

Higher Levels of High-Sensitivity C-Reactive Protein Is Positively Associated with the Incidence of Hyperuricemia in Chinese Population: A Report from the China Health and Retirement Longitudinal Study.

Hui-Xu Dai, Zhi-Ying Zhao, Yang Xia, Qi-Jun Wu, Yu-Hong Zhao

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hui-Xu DaiDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
Zhi-Ying ZhaoDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
Yang XiaDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
Qi-Jun WuDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
Yu-Hong ZhaoDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.ORCID https://orcid.org/0000-0002-6806-521X
China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of the present cohort study was to explore the longitudinal association between high-sensitivity C-reactive protein (CRP) and hyperuricemia in Chinese population. Furthermore, we conducted subgroup analyses to explore this association according to age, sex, and body mass index.

methodsA total of 5,419 healthy participants were enrolled in the final cohort analysis. The high-sensitivity CRP level was measured by immunoturbidimetric assay. Hyperuricemia was defined as serum uric acid ≥7.0 mg/dL (416

resultsDuring the 4 years follow-up, 474 participants developed hyperuricemia. Compared with participants in the lowest tertile of high-sensitivity CRP, the multivariate-adjusted odds ratio (OR) (95% confidence interval [CI]) for incident hyperuricemia in the highest tertile was 1.36 (1.02, 1.82). In the subgroup analyses, high-sensitivity CRP was positively associated with the incidence of hyperuricemia after multivariate adjustments (

conclusionsThe findings of this prospective cohort study suggest that higher level of high-sensitivity CRP is an independent risk factor for hyperuricemia in Chinese, especially in women.

Indexed as

AgedBiomarkersBody Mass IndexChinaC-Reactive ProteinFemaleHealthy VolunteersHumansHyperuricemiaImmunoturbidimetryIncidenceLongitudinal StudiesMaleMiddle AgedMultivariate AnalysisOdds RatioBiomarkersC-Reactive ProteinUric Acid

Identifiers

PMID32565724
PMCPMC7256734
OpenAlexW3027557007

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.