ArticleIndian journal of pharmacology
The effect of long-term valproic acid treatment in the level of total cholesterol among adult.
Article in Indian journal of pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Pre-treatment risk predictors of valproic acid-induced dyslipidemia in pediatric patients with epilepsy.Frontiers in pharmacology · 2024Article
- Distribution of Arteriosclerotic Vessels in Patients with Arteriosclerosis and the Differences of Serum Lipid Levels Classified by Different Sites.International journal of general medicine · 2024Article
- Valproate-Induced Metabolic Syndrome.Biomedicines · 2023Review
- Characteristics of serum lipid levels in patients with hypertension: a hospital-based retrospective descriptive study.BMJ open · 2022Article
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Authors and funding
2 authors.
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Abstract
Valproic acid (VA) is the antiepileptic, antimigraine and anti-mental disturbances agent. The use of VA is correlated to metabolic rearrangements including changes of lipoproteins; however, these effects still in debate. Herewith we analyze the effect of long-term VA treatment in the level of total cholesterol among adult. Sixty (30 case groups and 30 control groups) participants were asked for venous blood collection to examine the level of total cholesterol by enzymatic cholesterol oxidase phenol 4-aminoantipyrine peroxidase. The relationship of the long-term VA treatment and the level of total cholesterol was obtained from the analysis using the logistic regression analysis. Our analysis depicts that there is a relationship between the long-term VA treatment and the level of total cholesterol (P=0.024, odds ratio 0.272, 95% confidence interval 0.088-0.844). in conclusion, the long-term VA treatment reduces the level of total cholesterol in adult.
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