ArticleBMJ open2020
Study design and baseline characteristics of Shenzhen ageing-related disorder cohort in China.
Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- An unsupervised cluster analysis of multimorbidity patterns in older adults in Shenzhen, China.Frontiers in public health · 2025Article
- A systematic review and meta-analysis of the prevalence of Parkinson's disease in lower to upper-middle-income countries.NPJ Parkinson's disease · 2024Article
- The interaction effect of metals exposure and dietary habit on cognitive function in Chinese older adult cohort.The journal of nutrition, health & aging · 2024Article
- Urinary nicotine metabolites are associated with cognitive impairment among the elderly in southern China.Tobacco induced diseases · 2023Article
- The relative and interactive effects of urinary multiple metals exposure on hyperuricemia among urban elderly in China.Frontiers in public health · 2023Article
- Protein pyrrole adducts are associated with elevated glucose indices and clinical features of diabetic diffuse neuropathies.Journal of diabetes · 2022Article
- An alternative way of SARS-COV-2 to induce cell stress and elevated DNA damage risk in cardiomyocytes without direct infection.Immunity, inflammation and disease · 2022Article
- Diabetes mellitus is associated with elevated urinary pyrrole markers of γ-diketones known to cause axonal neuropathy.BMJ open diabetes research & care · 2020Article
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Authors and funding
22 authors.
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Abstract
purposeThe Shenzhen ageing-related disorder cohort was designed to detect the associations of lifestyle, environmental and genetic factors with major ageing-related disorders, especially neurological and mental disorders.
participantsThe cohort was a community-dwelling prospective study of 9411 elderly adults aged 60 to 92 years from 51 community health service centres in Luohu district of Shenzhen, China. The baseline data were collected between 2017 and 2018, including demographics and socioeconomics, lifestyles, medical history, family history of major non-communicable chronic disease, environmental exposures, clinical analysis of blood and urine, clinical imaging measurements, anthropometric measures and neurological function and mental health assessments. Blood and urinary samples were collected at baseline. All participants will be followed for physiological and psychological disorders and updated lifestyle and environmental exposures every 5 years. FINDINGS TO DATE: The mean age of the participants was 67.73 years at baseline, and 42.74% were males. The prevalences of individuals with unhealthy conditions were as follows: overweight/obesity (54.38%), hypertension (58.24%), diabetes mellitus (22.30%), dyslipidaemia (75.69%), chronic bronchitis (1.45%), myocardial infarction (0.55%), coronary heart disease (5.69%), stroke (1.10%), cancer (2.18%), arthritis (5.04%), Alzheimer's disease (0.18%), Parkinson's disease (0.23%), brain injury (5.75%), cognitive impairment (5.39%) and depression status (3.28%). The mean scores for the Lawton-Brody Activities of Daily Living Scale and the Social Support Rate Scale were 14.15 and 39.54, respectively. FUTURE PLANS: 2000 new entrants from Luohu district will be recruited every year until 2028. The data collection is expected to be ended at the end of 2030. The data will be used to assess the causality of ageing-related disorders, especially neurological and mental disorders through integrating environmental, genetic and lifestyle factors. The data sets generated and/or analysed during the current study are not publicly available at this stage, but are available from the corresponding author on reasonable request.
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