Evidence map›Paper›PMID 32564269›Full record

ArticleLa Radiologia medica2021

The value of DTI: achieving high diagnostic performance for brain metastasis.

Ma Liheng, Xu Guofan, Rosario Francesco Balzano, Liang Yuying, Hong Weifeng, Yang Ning, Ji Yayun, Liu Mouyuan, Giuseppe Guglielmi

Abstract read
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In one paragraph

Article in La Radiologia medica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Ma LihengImaging Department, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou City, Guangdong Province, China.
Xu GuofanDivision of Diagnostic Imaging, Department of Nuclear Medicine and Imaging Physics, MD Anderson Cancer Center, Houston City, TX, USA.
Rosario Francesco BalzanoDepartment of Clinical and Experimental Medicine, University School of Medicine, Viale L. Pinto, 1, 71121, Foggia, Italy.ORCID http://orcid.org/0000-0001-5630-6760
Liang YuyingImaging Department, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou City, Guangdong Province, China.
Hong WeifengImaging Department, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou City, Guangdong Province, China.
Yang NingPathology Department, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou City, Guangdong Province, China.
Ji YayunImaging Department, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou City, Guangdong Province, China.
Liu MouyuanImaging Department, First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou City, Guangdong Province, China.
Giuseppe GuglielmiDepartment of Clinical and Experimental Medicine, University School of Medicine, Viale L. Pinto, 1, 71121, Foggia, Italy. giuseppe.guglielmi@unifg.it.
First Affiliated Hospital of Guangdong Pharmaceutical University · CNUniversity of Foggia · ITThe University of Texas MD Anderson Cancer Center · US

Funding

Guangdong Science and Technology Department 2014A020212304
6 · The paper itself

Abstract

backgroundThe evaluation of brain metastases generally requires post-contrast MRI exam, but some patients have contraindication to contrast medium administration. PURPOSE: To investigate the value of the MRI diffusion tensor imaging (DTI) for detection of metastatic brain tumor. MATERIALS AND

methodsWe retrospectively analyzed the MRI data from 23 patients (13 males and 10 females) with brain metastases. The MRI protocol consisted in T1WI, T2WI, post-contrast 3DT1WI and DTI images (b = 1000) sequences. The brain metastatic lesions were counted in each of these sequences. We compared the advantages and limitations of different sequences in the brain metastases detection. The number of metastatic lesions identified on the contrast-enhanced 3DT1WI image is used as the reference. FA values were measured in the intratumoral, adjacent peritumoral and distant peritumoral edema area (PTEA) of brain metastasis, and the differences were statistically analyzed.

resultsDTI can detect more brain metastatic lesions rather than T1WI and T2WI. The number of brain metastases on DTI is similar to post-contrast 3D T1WI. There is no statistical difference in the FA value change between the adjacent and distant PTEA.

conclusionThe DTI original image can be used as an alternative examination for patients with contraindications to contrast-enhanced MRI. It has high sensitivity to intratumoral hemorrhage, which has advantage to detect brain metastatic lesions as compared with T1WI or T2WI images.

Indexed as

Brain NeoplasmsContrast MediaDiffusion Tensor ImagingFemaleHumansImaging, Three-DimensionalMaleMiddle AgedRetrospective StudiesContrast MediaBrain metastasesDiffusion tensor imaging (DTI)Magnetic resonance imaging (MRI)Post-contrast Imaging

Identifiers

PMID32564269
OpenAlexW3036163107

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.