Evidence map›Paper›PMID 32564204›Full record

SynthesisHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2020

The Influence of Fasting and Energy Restricting Diets on Blood Pressure in Humans: A Systematic Review and Meta-Analysis.

Hamed Kord-Varkaneh, Ali Nazary-Vannani, Zeinab Mokhtari, Ammar Salehi-Sahlabadi, Jamal Rahmani, Cain C T Clark, Somaye Fatahi, Fernando Zanghelini, Azita Hekmatdoost, Kehinde Okunade and 1 more

Open access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Diet, gut microbiota, and health: a review.Food science and biotechnology · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Chrononutrition in Cardiometabolic Health.Journal of clinical medicine · 2022
    Review
  12. Article
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 4 countries.

Hamed Kord-VarkanehStudent Research Committee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ali Nazary-VannaniDepartment of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Zeinab MokhtariFood Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Ammar Salehi-SahlabadiStudent Research Committee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Jamal RahmaniStudent Research Committee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Cain C T ClarkCentre for Sport, Exercise and Life Sciences, Coventry University, Coventry, CV15FB, UK.
Somaye FatahiStudent Research Committee, Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Fernando ZangheliniPostgraduate Program in Therapeutic Innovation, Federal University of Pernambuco, Pernambuco, Brazil.
Azita HekmatdoostStudent Research Committee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Kehinde OkunadeOncology and Pathological Studies (OPS) Unit, Department of Obstetrics and Gynaecology, College of Medicine, University of Lagos University Teaching Hospital, PMB 12003, Lagos, Nigeria.
Parvin MirmiranNutrition and Endocrine Research Center, Research Institute for Endocrine Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran. mirmiran@endocrine.ac.ir.
Shahid Beheshti University of Medical Sciences · IRNational Nutrition and Food Technology Research Institute · IRCoventry University · GBIran University of Medical Sciences · IRIsfahan University of Medical Sciences · IRTehran University of Medical Sciences · IRUniversidade Federal de Pernambuco · BRUniversity of Lagos · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo the best of our knowledge, no comprehensive meta-analysis has been carried out to investigate the effect of different approaches of fasting and calorie restriction on blood pressure. 

aimThus, the present systematic review and meta-analysis was designed to examine the effect of fasting and energy restricting diets on blood pressure in adult subjects.

methodsWe searched PubMed/Medline, Scopus, the Cochrane Library, and Google Scholar up to June 2019. The clinical trials that examined the effects of fasting and energy restricting diets on Blood Pressure was identified using MESH and non-MESH terms.

results23 studies, including a total of 1397 participants, reported SBP and DBP as an outcome measure. Overall results from the random-effects model indicated that fasting and energy restricting administration elicited significant changes in SBP (weight mean difference (WMD): - 1.88 mmHg, 95% CI - 2.50, - 1.25) and DBP (WMD - 1.32 mmHg, 95% CI - 1.81, - 0.84, p = 0.000). Subgroup analyses displayed that intervention duration ≤ 12 weeks more effectively reduced SBP (WMD: -3.26 mmHg) and DBP (WMD - 1.32 mmHg). In addition, these analyses showed that fasting regimens (WMD - 3.26 mmHg) more effectively reduced SBP than energy restricting diets (WMD - 1.09 mmHg).

conclusionThe principal finding of this study was that fasting and energy restricting diets elicited, overall, significant reductions in SBP and DBP. Subsequent subgroup analyses revealed that intervention duration ≤ 12 weeks and fasting regimens more effectively reduced SBP and DBP.

Indexed as

Blood PressureCaloric RestrictionFastingAdultFemaleHumansHypertensionMaleMiddle AgedTime FactorsTreatment OutcomeBlood pressureEnergy restrictingFastingMeta-analysis

Identifiers

PMID32564204
OpenAlexW3035943256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.