Evidence map›Paper›PMID 32564115›Full record

ArticleImmunogenetics2020

Latitudinal diversity gradient and cetaceans from the perspective of MHC genes.

Maria Luiza Andreani, Lucas Freitas, Elisa K S Ramos, Mariana F Nery

Abstract read
PubMed Publisher
In one paragraph

Article in Immunogenetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maria Luiza AndreaniLaboratório de Genômica Evolutiva, Departamento de Genética, Evolução, Microbiologia e Imunologia, Instituto de Biologia, Universidade Estadual de Campinas - UNICAMP, Rua Monteiro Lobato, 255, Cidade Universitária, IB, Bloco H, Campinas, SP, CEP 13083-862, Brazil.ORCID 0000-0002-1308-865X
Lucas FreitasLaboratório de Genômica Evolutiva, Departamento de Genética, Evolução, Microbiologia e Imunologia, Instituto de Biologia, Universidade Estadual de Campinas - UNICAMP, Rua Monteiro Lobato, 255, Cidade Universitária, IB, Bloco H, Campinas, SP, CEP 13083-862, Brazil.ORCID 0000-0002-8766-0890
Elisa K S RamosLaboratório de Genômica Evolutiva, Departamento de Genética, Evolução, Microbiologia e Imunologia, Instituto de Biologia, Universidade Estadual de Campinas - UNICAMP, Rua Monteiro Lobato, 255, Cidade Universitária, IB, Bloco H, Campinas, SP, CEP 13083-862, Brazil.ORCID 0000-0003-3600-820X
Mariana F NeryLaboratório de Genômica Evolutiva, Departamento de Genética, Evolução, Microbiologia e Imunologia, Instituto de Biologia, Universidade Estadual de Campinas - UNICAMP, Rua Monteiro Lobato, 255, Cidade Universitária, IB, Bloco H, Campinas, SP, CEP 13083-862, Brazil. mariananery@gmail.com.ORCID 0000-0001-6501-0486
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogen diversity is a key source of selective pressure on immune system genes, shaping molecular evolution mainly on widely distributed or migratory organisms such as cetaceans. Here, we investigated the effects of latitudinal span migration, different biomes occupation, and pathogen-mediated selection on MHC DQB locus divergence on cetaceans. We applied some evolutionary genetics methods using a dataset of 15 species and 121 sequences, and we found a trend on greater MHC divergence on tropical species when compared with either temperate or migratory species. In addition, oceanic cetaceans exhibit greater MHC divergence. Here, we show that, despite there was a correlation between the diversity of MHC DQB alleles with the distribution of organisms, the pattern of diversity found is not completely explained by pathogenic pressure, suggesting that other factors must be investigated for a better understanding of the processes related to the diversity of MHC in cetaceans.

Indexed as

Evolution, MolecularGenetic VariationSelection, GeneticAnimalsCetaceaEcosystemGenes, MHC Class IIPhylogenycetaceansevolutionlatitudinal gradientMHCmigration

Identifiers

PMID32564115
OpenAlexW3035836856

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.