ReviewInternational archives of allergy and immunology2020
The Role of Genetic Sex and Mitochondria in Response to COVID-19 Infection.
Review in International archives of allergy and immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed.
- Comparison of clinical characteristics and disease burden of febrile seizures in children with and without COVID-19.BMC pediatrics · 2024Article
- Chromosome-Y haplogroups in Asturias (Northern Spain) and their association with severe COVID-19.Molecular genetics and genomics : MGG · 2024Article
- Article
- Age- and Sex-Associated Pathogenesis of Cell Culture-Passaged Kemerovo Virus in IFNARInternational journal of molecular sciences · 2024Article
- Mitochondria in COVID-19: from cellular and molecular perspective.Frontiers in physiology · 2024Review
- SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress, and autophagic flux.iScience · 2023Article
- Exploration of the potential common pathogenic mechanisms in COVID-19 and silicosis by using bioinformatics and system biology.Functional & integrative genomics · 2023Article
- Article
- Active regression model for clinical grading of COVID-19.Frontiers in immunology · 2023Article
- Impacts of COVID-19 in Breast Cancer: From Molecular Mechanism to the Treatment Approach.Current pharmaceutical biotechnology · 2023Review
- Transcriptional differences between coronavirus disease 2019 and bacterial sepsis.Virology journal · 2022Article
- When the clock ticks wrong with COVID-19.Clinical and translational medicine · 2022Review
- Genetic and hormonal mechanisms underlying sex-specific immune responses in tuberculosis.Trends in immunology · 2022Review
- COVID-19 complications in males and females: recent developments.Journal of comparative effectiveness research · 2022Review
- SARS-CoV-2 Infection, Sex-Related Differences, and a Possible Personalized Treatment Approach with Valproic Acid: A Review.Biomedicines · 2022Review
- Immune Sexual Dimorphism: Connecting the Dots.Physiology (Bethesda, Md.) · 2022Review
- Identification of differentially expressed genes and their major pathways among the patient with COVID-19, cystic fibrosis, and chronic kidney disease.Informatics in medicine unlocked · 2022Article
- The Reserve/Maximum Capacity of Melatonin's Synthetic Function for the Potential Dimorphism of Melatonin Production and Its Biological Significance in Mammals.Molecules (Basel, Switzerland) · 2021Review
- Roles of host mitochondria in the development of COVID-19 pathology: Could mitochondria be a potential therapeutic target?Molecular biomedicine · 2021Review
- Cardiopulmonary exercise testing in COVID-19 patients at 3 months follow-up.International journal of cardiology · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The difference between the female and male immune response to COVID-19 infection, and infections in general, is multifactorial. The well-known determiners of the immune response, such as X and Y chromosomes, sex hormones, and microbiota, are functionally interconnected and influence each other in shaping the organism's immunity. We focus our commentary on the interplay between the genetic sex and mitochondria and how this may affect a sex-dependent immune response in COVID-19 infection. Realizing the existence of these interactions may help in designing novel methods or fine-tuning the existing and routine therapies to fight COVID-19 and other infections.
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Registered trials
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