Evidence map›Paper›PMID 32563970›Full record

ArticleMedical hypotheses2020

Deceiving SARS-CoV-2 molecular-tropism clues - A combinational contemporary strategy.

Apb Balaji, Srinivasan Bhuvaneswari, D Nanda Kumar

Open access · greenAbstract read
In one paragraph

Article in Medical hypotheses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.0field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Apb BalajiVanta Bioscience Limited, Gummidipoondi, Tamil Nadu, India; Ecoysus Life Science, Chennai, Tamil Nadu, India. Electronic address: balaji.apb15@gmail.com.
Srinivasan BhuvaneswariEcoysus Life Science, Chennai, Tamil Nadu, India; Department of Biotechnology, Anna University, Chennai, Tamil Nadu, India. Electronic address: mybiotech09@gmail.com.
D Nanda KumarEcoysus Life Science, Chennai, Tamil Nadu, India. Electronic address: d.nandamsc@gmail.com.
Anna University, Chennai · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several attempts to control the dreadfulness of SARS-CoV-2 are still underway. Based on the literature evidences we have speculated a prospective contemporary remedy, which was categorized into Specificity, Remedy, and a Conveyor. In which, pros and cons were discussed and inferred the possible alternatives. (a) Specificity: Implicit to express the ACE2 receptors in conveyor cells to deceive SARS-CoV-2 frompreponetargets. (b) Remedy: As depletion of pulmonary surfactants causes strong acute respiratory distress syndrome, we propose an entity of a cost-effective artificialsurfactantsystem as a remedy to pulmonary complications. (c) Conveyor: We propose red blood cells (RBCs) as a conveyor with embedded artificial surfactant and protruding ACE2 receptors for the target-specific delivery. Overall we postulate focused insights by employing a combinational contemporary strategy to steer towards a prospective direction on combating SARS-CoV-2.

Indexed as

ErythrocytesViral TropismAngiotensin-Converting Enzyme 2COVID-19Drug CostsDrug Delivery SystemsHumansPulmonary AlveoliPulmonary SurfactantsReceptors, VirusRespiratory Distress SyndromeSARS-CoV-2ACE2 protein, humanAngiotensin-Converting Enzyme 2Pulmonary SurfactantsReceptors, VirusACE2 receptorsARDSCoronavirusCOVID-19Molecular tropismPulmonary surfactantSARS-CoV-2

Identifiers

PMID32563970
PMCPMC7276125
OpenAlexW3033607177

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.