Evidence map›Paper›PMID 32563861›Full record

ArticleCell calcium2020

To B, or not to B: Is calcium the answer?

Yin-Hu Wang, Anthony Y Tao, Stefan Feske

Open access · greenAbstract read
In one paragraph

Article in Cell calcium, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yin-Hu WangDepartment of Pathology, New York University School of Medicine, New York, NY, USA.
Anthony Y TaoDepartment of Pathology, New York University School of Medicine, New York, NY, USA.
Stefan FeskeDepartment of Pathology, New York University School of Medicine, New York, NY, USA. Electronic address: feskes01@nyumc.org.
New York University · US

Funding

CRAC Channel Deficiency in Immunity to InfectionR01AI097302 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2012 to 2022
$5.6M
Regulation of Follicular T cell Responses in the Lung by Ion ChannelsR01AI130143 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2017 to 2021
$2.4M
Regulation of encephalitogenic T cells by CRAC channelsR01AI137004 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2018 to 2022
$2.4M
NIAID NIH HHS R01 AI097302NIAID NIH HHS R01 AI130143NIAID NIH HHS R01 AI137004
6 · The paper itself

Abstract

B lymphocytes are an important component of the adaptive and innate immune system because of their ability to secrete antibodies and to present antigens to T cells, which is critical for immune responses to many pathogens. Abnormal B cell function is the cause of diseases including autoimmune, paraneoplastic, and immunodeficiency disorders. The development, survival, and function of B cells depend on signaling through the B cell receptor (BCR) and costimulatory receptors. One of the signaling pathways induced by antigen binding to the BCR is store-operated Ca

Indexed as

AnimalsB-LymphocytesCalciumCalcium SignalingCell ProliferationCell SurvivalHumansImmunity, HumoralMiceCalciumApoptosisB cellsCalciumCRACmTORC1NFATNF-kappaBSTIM1STIM2

Identifiers

PMID32563861
PMCPMC7483609
OpenAlexW3033029526

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.