ArticleJACC. Cardiovascular imaging2020
Cardiac Magnetic Resonance Feature Tracking Global Longitudinal Strain and Prognosis After Heart Transplantation.
Article in JACC. Cardiovascular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Cardiac magnetic resonance in heart transplant recipients: histological, clinical and cell-free DNA validation.European heart journal. Cardiovascular Imaging · 2025Trial
- Role of Cardiovascular Magnetic Resonance in Post-Heart Transplant Surveillance: Integrating Evidence with Prospective Cohort Data.Journal of personalized medicine · 2026Article
- Review
- Utilizing cardiac magnetic resonance to assess the sequelae of prior rejection episodes on myocardium and correlation with clinical outcomes.JHLT open · 2025Article
- Enhanced risk stratification in chronic coronary syndrome using the left atrioventricular coupling index.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Long-term prognostic value of left and right ventricular systolic function on cardiovascular magnetic resonance imaging in systemic sclerosis.European heart journal. Cardiovascular Imaging · 2025Article
- Incremental value of multiparametric cardiac magnetic resonance imaging for non-invasive identification of significant acute cardiac allograft rejection: a prospective and biopsy-proven study.European heart journal. Cardiovascular Imaging · 2025Article
- Left Ventricular 3-Dimensional Global Longitudinal Strain Predicts All-Cause Mortality in Patients With Heart Transplant.Journal of the American Heart Association · 2024Article
- Prognostic Value of Left Ventricular Myocardial Strain Parameters Derived from Cardiac Magnetic Resonance Feature Tracking Technique in Light-Chain Cardiac Amyloidosis Patients: A Pilot Study.Reviews in cardiovascular medicine · 2024Article
- Interdependence between myocardial deformation and perfusion in patients with T2DM and HFpEF: a feature-tracking and stress perfusion CMR study.Cardiovascular diabetology · 2024Article
- Impact of pretransplant T2DM on left ventricular deformation and myocardial perfusion in heart transplanted recipients: a 3.0 T cardiac magnetic resonance study.Cardiovascular diabetology · 2024Article
- Right Ventricular Function on Cardiovascular Magnetic Resonance Imaging and Long-Term Outcomes in Stable Heart Transplant Recipients.Circulation. Cardiovascular imaging · 2024Article
- New Non-Invasive Imaging Technologies in Cardiac Transplant Follow-Up: Acquired Evidence and Future Options.Diagnostics (Basel, Switzerland) · 2023Review
- Clinical Utility of Strain Imaging in Assessment of Myocardial Fibrosis.Journal of clinical medicine · 2023Review
- Impact of myocardial deformation on risk prediction in patients following acute myocardial infarction.Frontiers in cardiovascular medicine · 2023Article
- Myocardial mechanics in dilated cardiomyopathy: prognostic value of left ventricular torsion and strain.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021Article
- Automated segmentation of biventricular contours in tissue phase mapping using deep learning.NMR in biomedicine · 2021Article
- Detection of cardiac allograft vasculopathy by multi-layer left ventricular longitudinal strain in heart transplant recipients.The international journal of cardiovascular imaging · 2021Article
- Myocardial damage assessed by late gadolinium enhancement on cardiovascular magnetic resonance imaging in cancer patients treated with anthracyclines and/or trastuzumab.European heart journal. Cardiovascular Imaging · 2021Article
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Abstract
objectivesThis study determined the long-term prognostic significance of GLS assessed using CMR-FT in a large cohort of heart transplant recipients.
backgroundIn heart transplant recipients, global longitudinal strain (GLS) assessed using echocardiography has shown promise in the prediction of clinical outcomes. We hypothesized that CMR feature tracking (CMR-FT) GLS is independently associated with long-term outcomes in heart transplant recipients.
methodsIn a cohort of consecutive heart transplant recipients who underwent routine CMR for clinical surveillance, CMR-FT GLS was calculated from 3 long-axis cine CMR images. Associations between GLS and a composite endpoint of death or major adverse cardiac events (MACE), including retransplantation, nonfatal myocardial infarction, coronary revascularization, and heart failure hospitalization, were investigated.
resultsA total of 152 heart transplant recipients (age 54 ± 15 years; 29% women; 5.0 ± 5.4 years after heart transplantation) were included. The median GLS was -11.6% (interquartile range: -13.6% to -9.2%). Over a median follow-up of 2.6 years, 59 recipients reached the composite endpoint. On Kaplan-Meier analyses, recipients with GLS worse than the median had a higher estimated cumulative incidence of the composite endpoint compared with recipients with GLS better than the median (log rank p = 0.004). On multivariate Cox proportional hazards regression, GLS was independently associated with the composite endpoint after adjustment for cardiac allograft vasculopathy, history of rejection, left ventricular ejection fraction (LVEF), right ventricular EF, and presence of myocardial fibrosis, with a hazard ratio of 1.15 for every 1% worsening in GLS (95% confidence interval: 1.06 to 1.24; p < 0.001). Similar results were seen in subgroups of recipients with LVEF >50% and with no myocardial fibrosis. GLS provided incremental prognostic value over other variables in the multivariate model as determined by the log-likelihood chi-squared test.
conclusionsIn a large cohort of heart transplant recipients, CMR-FT GLS was independently associated with the long-term risk of death or MACE.
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