ArticleInternational journal of health policy and management2020
How Useful Are Early Economic Models? Comment on "Problems and Promises of Health Technologies: The Role of Early Health Economic Modelling".
Article in International journal of health policy and management, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Headroom Analysis for Early Economic Evaluation: A Systematic Review.Applied health economics and health policy · 2023Pooled it
- Cost-Effectiveness of Personalised Nutrition in Adults With Overweight and Obesity: PREVENTOMICS Studies in Poland and the UK.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025Trial
- Early health technology assessment (eHTA) approaches focused on human stem cell-related technologies: a scoping review protocol.BMJ open · 2026Article
- Early health technology assessment of a primary care tool for the diagnosis and management of headaches in Alberta, Canada.International journal of technology assessment in health care · 2026Article
- An Early-Stage Decision-Analytic Health Economic Model of Above Cuff Vocalization: What Do We Know and What Do We Need to Resolve?Critical care explorations · 2025Article
- NICE's early value assessment: an external assessment group's commentary on the challenges and opportunities of NICE's new life cycle approach to HealthTech.International journal of technology assessment in health care · 2025Review
- Advances in Addressing Patient Heterogeneity in Economic Evaluation: A Review of the Methods Literature.PharmacoEconomics · 2024Review
- The role of economic evaluations in advancing HIV multipurpose prevention technologies in early-stage development.Frontiers in reproductive health · 2024Article
- Early Economic Assessment of Faecal Microbiota Transplantation for Patients with Urinary Tract Infections Caused by Multidrug-Resistant Organisms.Infectious diseases and therapy · 2023Article
- Article
- Using early health economic modeling to inform medical innovation development: a soft robotic sock in poststroke patients in Singapore.International journal of technology assessment in health care · 2023Article
- Early economic modeling of magnetic resonance image-guided high intensity focused ultrasound compared to radiotherapy for pain palliation of bone metastases.Frontiers in oncology · 2022Article
- Implementation of Magnetic Resonance Imaging-Guided Radiation Therapy in Routine Care: Opportunities and Challenges in the United States.Advances in radiation oncologyArticle
Corrections and comments
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1 author.
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No grant is acknowledged in the PubMed record.
Abstract
Early economic modelling has long been recommended to aid research and development (R&D) decisions in medical innovation, although they are less frequently published and critically appraised. A review of 30 innovations by Grutters et al provides an opportunity to evaluate how early models are used in practice. The evidence of early models can be used to inform two types of decision: to continue development ("stop or go") or to alter future R&D activities. I argue that early models have limited use in stop or go decisions, as less resource and data undermine the reliability of the models' indicative estimates of cost-effectiveness. Whilst they are far more useful for informing future R&D directions, the best techniques available from statistical decision science, such as value of information analysis, are not regularly used. It is highly recommended that early models adopt these methods to best deal with uncertainty, quantify the potential value of further research, identify areas of study with the greatest potential benefit and generate recommendations on study design and sample size.
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