Evidence map›Paper›PMID 32563019›Full record

ReviewAmerican journal of otolaryngology

COVID-19 and anosmia: A review based on up-to-date knowledge.

Xiangming Meng, Yanzhong Deng, Zhiyong Dai, Zhisheng Meng

5 registry-linked trialsOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in American journal of otolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 189 papers, 18 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
189citing papers in PubMed, 18 pooled it
29.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04789499 phase2completednot on this map

Smell in Covid-19 and Efficacy of Nasal Theophylline

TypeinterventionalSponsorWashington University School of MedicineRan2021 to 2021Enrolled51ConditionsCovid19, Anosmia, Olfactory Disorder, Covid-19 PandemicArmsTheophylline Powder, Placebo Comparator
NCT05216614 phase2withdrawnnot on this map

Fluvoxamine to Augment Olfactory Recovery For Long COVID-19 Parosmia (FluCOP Trial)

TypeinterventionalSponsorWashington University School of MedicineRan2021 to 2022Enrolled0ConditionsCOVID-19, Olfactory Disorder, ParosmiaArmsFluvoxamine, Placebo
NCT05379556 recruitingnot on this map

LOng COvid COmorbidities: Evaluation of Andrological, Reproductive and Sexual Functions in Patients Recovered From COVID-19

TypeobservationalSponsorFederico II UniversityRan2022 to 2027Enrolled100ConditionsLong Covid-19ArmsAssessment of andrological profile of LO-COCO-ANDRO male patients, Assessment of reproductive function of LO-COCO-ANDRO male patients, Assessment of sexual function of LO-COCO-ANDRO male patients, Assessment of olfactory function of LO-COCO-ANDRO male and female patients
NCT05947643 phase2completednot on this map

Smell in COVID-19 and Efficacy of Nasal Theophylline 3

TypeinterventionalSponsorWashington University School of MedicineRan2022 to 2025Enrolled77ConditionsCOVID-19Armstheophylline, Placebo
NCT06789952 naterminatednot on this map

Mindfulness-Based Stress Reduction (MBSR) Versus Lifestyle Intervention for Long-Haul Covid-19 Parosmia (LCP)

TypeinterventionalSponsorWashington University School of MedicineRan2023 to 2023Enrolled41ConditionsCOVID-19ArmsMindfulness-Based Stress Reduction, Lifestyle Intervention
3 · Its place in the literature

Who cites it

189 citing papers in PubMed, 18 syntheses or guidelines pooled it, 421 citations in OpenAlex.

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  4. Inhaled corticosteroids' effect on COVID-19 patients: A systematic review and meta-analysis of randomized controlled trials.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2023
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  7. Efficacy of topical steroids for the treatment of olfactory disorders caused by COVID-19: A systematic review and meta-analysis.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2022
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  19. Trial
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129 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Xiangming MengDepartment of Otolaryngology, Wuxi Huishan District People's Hospital, 2 Zhanqian North Road, Luoshe Town, Huishan District, Wuxi 214187, PR China. Electronic address: xiangming_meng@hotmail.com.
Yanzhong DengDepartment of Anesthesiology, Wuxi Huishan District People's Hospital, 2 Zhanqian North Road, Luoshe Town, Huishan District, Wuxi 214187, PR China.
Zhiyong DaiDepartment of Otolaryngology, Wuxi Huishan District People's Hospital, 2 Zhanqian North Road, Luoshe Town, Huishan District, Wuxi 214187, PR China.
Zhisheng MengFaculty of Information Engineering and Automation, Kunming University of Science and Technology, No.727 South Jingming Road, Chenggong District, Kunming 650500, PR China.
Kunming University of Science and Technology · CNThe People's Hospital of LinXia · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pandemic of Coronavirus Disease 2019 (COVID-19) has caused a vast disaster throughout the world. There is increasing evidence that olfactory dysfunction can present in COVID-19 patients. Anosmia can occur alone or can be accompanied by other symptoms of COVID-19, such as a dry cough. However, the pathogenic mechanism of olfactory dysfunction and its clinical characteristics in patients with COVID-19 remains unclear. Multiple cross-sectional studies have demonstrated that the incidence rate of olfactory dysfunction in COVID-19 patients varies from 33.9-68% with female dominance. Anosmia and dysgeusia are often comorbid in COVID-19 patients. Otolaryngologists should be mindful of the symptom of anosmia in outpatients so as not to delay the diagnosis of COVID-19. In this paper, we have reviewed the relevant knowledge based on up-to-date literature.

Indexed as

BetacoronavirusCoronavirus InfectionsCOVID-19HumansOlfaction DisordersPandemicsPneumonia, ViralSARS-CoV-2AnosmiaCoronavirusCOVID-19Olfactory dysfunctionOtolaryngologySARS-CoV-2Smell

Identifiers

PMID32563019
PMCPMC7265845
OpenAlexW3028801636

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.