ArticleClinical imaging2020
Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome: Spectrum of imaging findings.
Article in Clinical imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Birt-Hogg-Dubé: CT characteristics of renal tumors in a rare syndrome.Abdominal radiology (New York) · 2026Article
- Hereditary syndromes and RCC: what radiologists need to know.Abdominal radiology (New York) · 2026Review
- Characterization of complex renal cysts in hereditary leiomyomatosis and renal cell cancerUsing magnetic resonance based qualitative features.Abdominal radiology (New York) · 2026Article
- Hereditary leiomyomatosis and renal cell carcinoma: a case report and literature review.Frontiers in urology · 2026Article
- Morphological analysis of peritoneal fluid in fumarate hydratase deficiency-associated renal cell carcinoma: a case report.Frontiers in oncology · 2025Article
- Article
- Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) Syndrome.Journal of the Belgian Society of Radiology · 2024Article
- Review
- Role of ultra-high b-value DWI in the imaging of hereditary leiomyomatosis and renal cell carcinoma (HLRCC).Abdominal radiology (New York) · 2023Article
- Single-cell transcriptomes underscore genetically distinct tumor characteristics and microenvironment for hereditary kidney cancers.iScience · 2022Article
- Multidetector CT Characteristics of Fumarate Hydratase-Deficient Renal Cell Carcinoma and Papillary Type II Renal Cell Carcinoma.Korean journal of radiology · 2021Article
- Bosniak classification of cystic renal masses, version 2019: interpretation pitfalls and recommendations to avoid misclassification.Abdominal radiology (New York) · 2021Review
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11 authors.
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Abstract
purposeTo retrospectively investigate the radiological presentations of HLRCC-associated renal tumors to facilitate accurate lesion characterization and compare these presentations with simple cysts and characteristics of other subtypes of renal cell carcinoma (RCC) as reported in the literature.
methodsThe MRI and CT imaging characteristics of 39 pathologically confirmed lesions from 30 patients (20 male, 10 female) with HLRCC syndrome were evaluated by two radiologists. Patients had an average age at diagnosis of 43.8 ± 13.1 years. Lesion characteristics including laterality, homogeneity, diameter (cm), nodularity, septations, T1 and T2 signal intensity, enhancement, and restricted diffusion were recorded. Imaging characteristics of the lesions were further compared to characteristics of benign simple cysts surgically removed at the same time point.
resultsThe examined lesions had a mean diameter of 5.06 ± 3.80 cm, an average growth rate of 2.91 × 10
conclusionsOur analysis confirmed that while HLRCC-associated renal lesions demonstrate diversity in imaging presentations, the majority are unilateral and solitary, T2-hyperintense, heterogeneous with well-defined margins, and frequently demonstrate restricted diffusion and nodularity.
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