ArticleNeuron2020
Different Multidimensional Representations across the Amygdalo-Prefrontal Network during an Approach-Avoidance Task.
Article in Neuron, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Complementary stable and dynamic prelimbic ensembles encode learned threat value underlying generalization and discrimination.bioRxiv : the preprint server for biology · 2026Article
- A UNIFORM CODING STRUCTURE IN THE NEOCORTEX.bioRxiv : the preprint server for biology · 2026Article
- Regional specialization in prefrontal cortex manifests in the reliability of task progression codes.Neuron · 2026Article
- Article
- Divergent prefrontal cortex circuits regulate cued food seeking under distinct metabolic or emotional states.Nature communications · 2025Article
- Synaptic organization and associative learning-related activity of basolateral amygdala interneurons.Cell reports · 2025Article
- Collateralization patterns of principal basolateral amygdala neurons delineate distinct output streams.iScience · 2025Article
- Graded remapping of prefrontal representations preserves a cumulative record of distinct events within an environment.iScience · 2025Article
- Article
- Common Neocortical and Hippocampal Correlates of Performance Errors in a Timing Task.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Major individual and regional variations in unit entrainment by oscillations of different frequencies.Scientific reports · 2025Article
- Bidirectional valence coding in amygdala intercalated clusters: A neural substrate for the opponent-process theory of motivation.Neuroscience research · 2024Article
- Prefrontal projections to the bed nuclei of the stria terminalis modulate the specificity of aversive memories.Research square · 2024Article
- Population-level coding of avoidance learning in medial prefrontal cortex.Nature neuroscience · 2024Article
- Behavioral outputs and overlapping circuits between conditional fear and active avoidance.Neurobiology of learning and memory · 2024Review
- Genetically- and spatially-defined basolateral amygdala neurons control food consumption and social interaction.Nature communications · 2024Article
- Ventral Pallidum and Amygdala Cooperate to Restrain Reward Approach under Threat.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Prefrontal circuits encode both general danger and specific threat representations.Nature neuroscience · 2023Article
- Causally mapping human threat extinction relevant circuits with depolarizing brain stimulation methods.Neuroscience and biobehavioral reviews · 2023Review
- A Goldilocks theory of cognitive control: Balancing precision and efficiency with low-dimensional control states.Current opinion in neurobiology · 2022Review
Corrections and comments
- Commented on by
Authors and funding
3 authors.
Funding
Abstract
The prelimbic (PL) area and basolateral amygdala (lateral [LA] and basolateral [BL] nuclei) have closely related functions and similar extrinsic connectivity. Reasoning that the computational advantage of such redundancy should be reflected in differences in how these structures represent information, we compared the coding properties of PL and amygdala neurons during a task that requires rats to produce different conditioned defensive or appetitive behaviors. Rather than unambiguous regional differences in the identities of the variables encoded, we found gradients in how the same variables are represented. Whereas PL and BL neurons represented many different parameters through minor variations in firing rates, LA cells coded fewer task features with stronger changes in activity. At the population level, whereas valence could be easily distinguished from amygdala activity, PL neurons could distinguish both valence and trial identity as well as or better than amygdala neurons. Thus, PL has greater representational capacity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.