Evidence map›Paper›PMID 32562310›Full record

Trial reportMolecular nutrition & food research2020

Impact of Phenol-Enriched Virgin Olive Oils on the Postprandial Levels of Circulating microRNAs Related to Cardiovascular Disease.

Lidia Daimiel, Víctor Micó, Rosa M Valls, Anna Pedret, María José Motilva, Laura Rubió, Montse Fitó, Marta Farrás, María Isabel Covas, Rosa Solá and 1 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Molecular nutrition & food research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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  16. Atherosclerosis: From Molecular Biology to Therapeutic Perspective 3.0.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Lidia DaimielNutritional Control of the Epigenome Group, Instituto Madrileño de Estudios, Avanzados (IMDEA) Food Institute, CEI UAM+CSIC, Madrid, 28049, Spain.ORCID 0000-0001-9898-6629
Víctor MicóNutritional Control of the Epigenome Group, Instituto Madrileño de Estudios, Avanzados (IMDEA) Food Institute, CEI UAM+CSIC, Madrid, 28049, Spain.
Rosa M VallsFunctional Nutrition, Oxidation and Cardiovascular Disease Research Group, Universitat Rovira i Virgili, Hospital Universitari Sant Joan, EURECAT, Reus, 43204, Spain.ORCID 0000-0002-3351-0942
Anna PedretFunctional Nutrition, Oxidation and Cardiovascular Disease Research Group, Universitat Rovira i Virgili, Hospital Universitari Sant Joan, EURECAT, Reus, 43204, Spain.
María José MotilvaFood Technology Department, Agrotecnio Center, Escola Tècnica Superior d'Enginyeria Agrària, University of Lleida, Lleida, 25198, Spain.
Laura RubióInstituto de Ciencias de la Vid y del Vino-ICVV, (CSIC-Consejo Superior de Investigaciones Científicas, Universidad de La Rioja, Gobierno de La Rioja), Finca La Grajera, Ctra. de Burgos Km. 6 (LO-20 - salida 13), Logroño, La Rioja, 26007, Spain.
Montse FitóCardiovascular Risk and Nutrition (Regicor Study Group), Hospital del Mar Medical Research Institute (IMIM), 08003 Barcelona, Spain. CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, 28029, Spain.
Marta FarrásCardiovascular Risk and Nutrition (Regicor Study Group), Hospital del Mar Medical Research Institute (IMIM), 08003 Barcelona, Spain. CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, 28029, Spain.
María Isabel CovasCardiovascular Risk and Nutrition (Regicor Study Group), Hospital del Mar Medical Research Institute (IMIM), 08003 Barcelona, Spain. CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, 28029, Spain.
Rosa SoláFunctional Nutrition, Oxidation and Cardiovascular Disease Research Group, Universitat Rovira i Virgili, Hospital Universitari Sant Joan, EURECAT, Reus, 43204, Spain.
José M OrdovásNutritional Genomics and Epigenomics Group, Instituto Madrileño de Estudios Avanzados (IMDEA) Food Institute, CEI UAM+CSIC, Madrid, 28049, Spain.
Hospital Universitari Sant Joan de Reus · ESInstituto de Salud Carlos III · ESMadrid Institute for Advanced Studies · ESConsejo Superior de Investigaciones Científicas · ESUniversitat de Lleida · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

scopeWe investigate the postprandial modulation of cardiovascular-related microRNAs elicited by extra virgin olive oil (EVOOs) containing different levels of their own polyphenols. METHODS AND

resultsIt is randomized, postprandial, parallel, double-blind study. Twelve healthy participants consumed 30 mL of EVOO containing low (L-EVOO; 250 mg total phenols kg

conclusionDuring the postprandial state, the levels of let-7e-5p decrease with EVOO regardless of polyphenol content suggesting a general response to the fatty acid composition of EVOO or/and the presence of at least 250 mg polyphenol kg

Indexed as

AdultBlood GlucoseCardiovascular DiseasesCell-Free Nucleic AcidsComputer SimulationDouble-Blind MethodEndothelium, VascularFemaleFood, FortifiedHumansLipidsMaleMicroRNAsMiddle AgedOlive OilPhenolsBlood GlucoseCell-Free Nucleic AcidsLipidsMicroRNAsOlive OilPhenolsbiomarkerscardiovascular diseaseextra virgin olive oilmediterranean dietmicroRNAs

Identifiers

PMID32562310
PMCPMC7507201
OpenAlexW3036197489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.