Evidence map›Paper›PMID 32562188›Full record

Observational studyBreast cancer (Tokyo, Japan)2020

3-Dimensional objective aesthetic evaluation to replace panel assessment after breast-conserving treatment.

Amy R Godden, Rachel L O'Connell, Peter A Barry, Katherine C D Krupa, Lisa M Wolf, Kabir Mohammed, Anna M Kirby, Jennifer E Rusby

Open access · hybridAbstract readObservational StudyValidation Study
In one paragraph

Observational study in Breast cancer (Tokyo, Japan), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Amy R GoddenRoyal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, UK.ORCID http://orcid.org/0000-0001-9781-6097
Rachel L O'ConnellRoyal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, UK.
Peter A BarryInstitute of Cancer Research, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK.
Katherine C D KrupaRoyal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, UK.
Lisa M WolfRoyal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, UK.
Kabir MohammedRoyal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, UK.
Anna M KirbyRoyal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, UK.
Jennifer E RusbyRoyal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, UK. Jennifer.rusby@rmh.nhs.uk.
Royal Marsden NHS Foundation Trust · GBInstitute of Cancer Research · GB

Funding

Cancer Research UK 28284
6 · The paper itself

Abstract

backgroundTwo-thirds of patients with early breast cancer undergo breast-conserving treatment (BCT). Aesthetic outcome is important and has long term implications for psychosocial wellbeing. The aesthetic goal of BCT is symmetry for which there is no gold-standard measure. Panel scoring is the most widely adopted assessment but has well-described limitations. This paper describes a model to objectively report aesthetic outcome using measures derived from 3-dimensional surface images (3D-SI).

methodObjective measures and panel assessment were undertaken independently for 3D-SI of women who underwent BCT 1-5 years previously. Univariate analysis was used to test for association between measures and panel score. A forward stepwise multiple linear regression model was fitted to identify 3D measurements that jointly predicted the mean panel score. The fitted model coefficients were used to predict mean panel scores for an independent validation set then compared to the mean observed panel score.

resultsVery good intra-panel reliability was observed for the training and validation sets (wκ = 0.87, wκ = 0.84). Six 3D-measures were used in the multivariate model. There was a good correlation between the predicted and mean observed panel score in the training (n = 190) and validation (n = 100) sets (r = 0.68, r = 0.65). The 3D model tended to predict scores towards the median. The model was calibrated which improved the distribution of predicted scores.

conclusionA six-variable objective aesthetic outcome model for BCT has been described and validated. This can predict and could replace panel assessment, facilitating the independent and unbiased evaluation of aesthetic outcome to communicate and compare results, benchmark practice, and raise standards.

Indexed as

EstheticsImaging, Three-DimensionalAgedBreastBreast NeoplasmsCross-Sectional StudiesFemaleGoalsHumansLinear ModelsMastectomy, SegmentalMiddle AgedPatient SatisfactionQuality of LifeReproducibility of ResultsTreatment Outcome3D-SIAestheticsBreastCancerConservationSurgery

Identifiers

PMID32562188
PMCPMC7717038
OpenAlexW3036483577

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.