Evidence map›Paper›PMID 32562177›Full record

ReviewMycopathologia2020

Successful Terbinafine Treatment for Cutaneous Phaeohyphomycosis Caused by Trematosphaeria grisea in a Heart Transplanted Man: Case Report and Literature Review.

Victor Mercier, Frédéric Bastides, Éric Bailly, Dea Garcia-Hermoso, Elodie Miquelestorena-Standley, Zaki El Baz, Emilie Marteau, Emmanuelle Vermes, Anne De Muret, Louis Bernard and 1 more

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Mycopathologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Victor MercierParasitologie - Mycologie et Médecine Tropicale, Hôpital Bretonneau, CHU de Tours, 2 Boulevard Tonnellé, 37044, Tours, France. victor.mercier@gmail.com.
Frédéric BastidesMédecine Interne Et Maladies Infectieuses, CHU de Tours, Tours, France.
Éric BaillyParasitologie - Mycologie et Médecine Tropicale, Hôpital Bretonneau, CHU de Tours, 2 Boulevard Tonnellé, 37044, Tours, France.
Dea Garcia-HermosoCNRS, National Reference Center for Invasive Mycoses and Antifungals (NRCMA), Molecular Mycology Unit, UMR2000, Institut Pasteur, Paris, France.
Elodie Miquelestorena-StandleyAnatomie Et Cytologie Pathologiques, CHU de Tours, Chambray-les-Tours, France.
Zaki El BazRadiologie, CHU de Tours, Chambray-les-Tours, France.
Emilie MarteauChirurgie orthopédique Et Traumatologie, CHU de Tours, Chambray-les-Tours, France.
Emmanuelle VermesChirurgie Cardiaque, CHU de Tours, Tours, France.
Anne De MuretAnatomie Et Cytologie Pathologiques, CHU de Tours, Chambray-les-Tours, France.
Louis BernardMédecine Interne Et Maladies Infectieuses, CHU de Tours, Tours, France.
Guillaume DesoubeauxParasitologie - Mycologie et Médecine Tropicale, Hôpital Bretonneau, CHU de Tours, 2 Boulevard Tonnellé, 37044, Tours, France.ORCID http://orcid.org/0000-0001-7945-9890
Centre Hospitalier Universitaire de Tours · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phaeohyphomycosis is a chronic infectious disease caused by dematiaceous fungi. It is characterized by the presence of pigmented septate mycelia within tissues. In the case of superficial infection, the lesion(s) chronically evolve(s) toward painless pseudo-tumor(s) of the soft parts. We report herein the original case of a heart transplanted man who exhibited phaeohyphomycosis of the left hand, with no mention of travels in endemic areas. Trematosphaeria grisea was identified as the causative agent, which is quite innovative since this species has been rather described in mycetoma. The antifungal treatment initially based on isavuconazole alone was not sufficient to cure the patient. In contrast, its association with local terbinafine ointment allowed total clinical improvement. This finding is unusual as diagnosis of phaeohyphomycosis caused by T. grisea is uncommon in nontropical countries, and as the outcome appeared successful by the means of add-on therapeutic strategy with terbinafine.

Indexed as

Antifungal AgentsAscomycotaPhaeohyphomycosisHeart TransplantationHumansMaleTerbinafineTransplant RecipientsAntifungal AgentsTerbinafineDematiaceous fungusIsavuconazolePhaeohyphomycosisTerbinafineTrematosphaeria grisea

Identifiers

PMID32562177
OpenAlexW3036266009

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.