ArticleThe Journal of clinical endocrinology and metabolism2020
Pediatric Reference Ranges for Ultradistal Radius Bone Density: Results from the Bone Mineral Density in Childhood Study.
Article in The Journal of clinical endocrinology and metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
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- Phthalates exposure and longitudinal trajectories of body composition and regional fat distribution in children: shifting towards "apple-shaped" body and the role of physical activity.BMC public health · 2025Article
- Correlation Analysis between Serum Uric Acid Levels and Bone Mineral Density in Children with Obesity.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- The life-course changes in muscle mass using dual-energy X-ray absorptiometry: The China BCL study and the US NHANES study.Journal of cachexia, sarcopenia and muscle · 2024Article
- Reference ranges for body composition indices by dual energy X-ray absorptiometry from the Bone Mineral Density in Childhood Study Cohort.The American journal of clinical nutrition · 2023Observational
- Bone health in avoidant/restrictive food intake disorder: a narrative review.Journal of eating disorders · 2023Review
- Associations of maternal gestational urinary environmental phenols concentrations with bone mineral density among 12-year-old children in the HOME Study.International journal of hygiene and environmental health · 2023Article
- Early life organophosphate ester exposures and bone health at age 12 years: The Health Outcomes and Measures of the Environment (HOME) Study.The Science of the total environment · 2022Article
- An update on methods for assessing bone quality and health in Cystic fibrosis.Journal of clinical & translational endocrinology · 2022Article
- Utility and validation of bone mineral density measurements at forearm in predicting trabecular microarchitecture and central-site osteoporosis in aging Indian postmenopausal women-a promising surrogate?Aging medicine (Milton (N.S.W)) · 2022Article
- Bone Mineral Density and Current Bone Health Screening Practices in Friedreich's Ataxia.Frontiers in neuroscience · 2022Article
- Article
- Deficits in the Functional Muscle-Bone Unit in Youths with Fontan Physiology.The Journal of pediatrics · 2021Article
- Associations of Maternal Serum Perfluoroalkyl Substances Concentrations with Early Adolescent Bone Mineral Content and Density: The Health Outcomes and Measures of the Environment (HOME) Study.Environmental health perspectives · 2021Article
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Authors and funding
9 authors at 7 institutions in 1 country.
Funding
Abstract
contextThe ultradistal (UD) radius is rich in trabecular bone and is easily measured by dual energy X-ray absorptiometry (DXA). UD radius areal bone mineral density (aBMD) may help identify trabecular bone deficits, but reference data are needed for research and clinical interpretation of this measure.
objectiveWe developed age-, sex-, and population ancestry-specific reference ranges for UD radius aBMD assessed by DXA and calculated Z-scores. We examined tracking of UD radius aBMD Z-scores over 6 years and determined associations between UD radius aBMD Z-scores and other bone measures by DXA and peripheral quantitative computed tomography.
designMulticenter longitudinal study.
participantsA total of 2014 (922 males, 22% African American) children ages 5 to 19 years at enrollment who participated in the Bone Mineral Density in Childhood Study.
main outcome measureUD radius aBMD.
resultsUD radius aBMD increased nonlinearly with age (P < 0.001) and tended to be greater in males versus females (P = 0.054). Age-, sex-, and ancestry-specific UD radius aBMD reference curves were constructed. UD radius aBMD Z-scores positively associated with Z-scores at other skeletal sites (r = 0.54-0.64, all P < 0.001) and peripheral quantitative computed tomography measures of distal radius total volumetric BMD (r = 0.68, P < 0.001) and trabecular volumetric BMD (r = 0.70, P < 0.001), and was weakly associated with height Z-score (r = 0.09, P = 0.015). UD radius aBMD Z-scores tracked strongly over 6 years, regardless of pubertal stage (r = 0.66-0.69; all P < 0.05).
conclusionUD radius aBMD Z-scores strongly associated with distal radius trabecular bone density, with marginal confounding by stature. These reference data may provide a valuable resource for bone health assessment in children.
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