Evidence map›Paper›PMID 32561887›Full record

ArticleCommunications biology2020

Genomic signatures of domestication in Old World camels.

Robert Rodgers Fitak, Elmira Mohandesan, Jukka Corander, Adiya Yadamsuren, Battsetseg Chuluunbat, Omer Abdelhadi, Abdul Raziq, Peter Nagy, Chris Walzer, Bernard Faye and 1 more

Abstract read
In one paragraph

Article in Communications biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Methylation-associated mutagenesis underlies variation in the mutation spectrum across eukaryotes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Article
  8. The power of coalescent methods for inferring recent and ancient gene flow in endangered Bactrian camels.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Phenotype transition from wild mouflon to domestic sheep.Genetics, selection, evolution : GSE · 2024
    Review
  14. Review
  15. Article
  16. Sequencing and Characterization of αs2-Casein Gene (Animals : an open access journal from MDPI · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Robert Rodgers FitakInstitute of Population Genetics, Vetmeduni Vienna, Veterinärplatz 1, 1210, Vienna, Austria. rfitak9@gmail.com.ORCID http://orcid.org/0000-0002-7398-6259
Elmira MohandesanInstitute of Population Genetics, Vetmeduni Vienna, Veterinärplatz 1, 1210, Vienna, Austria.
Jukka CoranderWellcome Sanger Institute, Hinxton, UK.
Adiya YadamsurenInstitute of Remote Sensing and Digital Earth, Chinese Academy of Sciences, Jia No.20 North, DaTun road, ChaoYang District, Beijing, China.
Battsetseg ChuluunbatLaboratory of Genetics, Institute of General and Experimental Biology, Mongolian Academy of Sciences, Peace avenue-54b, Bayarzurh District, Ulaanbaatar, 210351, Mongolia.
Omer AbdelhadiUniversity of Khartoum, Department for Meat Sciences, Khartoum, Sudan.
Abdul RaziqCamelait, Alain Farms for Livestock Production, Alain Dubai Road, Alain, United Arab Emirates.ORCID http://orcid.org/0000-0001-9464-9465
Peter NagyFarm and Veterinary Department, Emirates Industry for Camel Milk and Products, PO Box 294236, Dubai, Umm Nahad, United Arab Emirates.ORCID http://orcid.org/0000-0001-7068-9489
Chris WalzerWildlife Conservation Society, Wildlife Health Program, Bronx, NY, USA.ORCID http://orcid.org/0000-0002-0437-5147
Bernard FayeCIRAD-ES, UMR 112, Campus International de Baillarguet, TA C/112A, 34398, Montpellier, France.ORCID http://orcid.org/0000-0002-5762-5453
Pamela Anna BurgerInstitute of Population Genetics, Vetmeduni Vienna, Veterinärplatz 1, 1210, Vienna, Austria. Pamela.burger@vetmeduni.ac.at.ORCID http://orcid.org/0000-0002-6941-0257

Funding

Austrian Science Fund FWF P 24706Austrian Science Fund FWF P24706-B25Austrian Science Fund FWF P 29623Austrian Science Fund FWF P29623-B25
6 · The paper itself

Abstract

Domestication begins with the selection of animals showing less fear of humans. In most domesticates, selection signals for tameness have been superimposed by intensive breeding for economical or other desirable traits. Old World camels, conversely, have maintained high genetic variation and lack secondary bottlenecks associated with breed development. By re-sequencing multiple genomes from dromedaries, Bactrian camels, and their endangered wild relatives, here we show that positive selection for candidate genes underlying traits collectively referred to as 'domestication syndrome' is consistent with neural crest deficiencies and altered thyroid hormone-based signaling. Comparing our results with other domestic species, we postulate that the core set of domestication genes is considerably smaller than the pan-domestication set - and overlapping genes are likely a result of chance and redundancy. These results, along with the extensive genomic resources provided, are an important contribution to understanding the evolutionary history of camels and the genomic features of their domestication.

Indexed as

Selection, GeneticAnimalsCamelusDomesticationGenetics, PopulationGenetic VariationGenomeGermaniumOrganometallic CompoundsPolymorphism, Single NucleotidePropionatesWhole Genome SequencingGermaniumOrganometallic CompoundspropagermaniumPropionates

Identifiers

PMID32561887
PMCPMC7305198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.