ArticleNature communications2020
Rapid fast-delta decay following prolonged wakefulness marks a phase of wake-inertia in NREM sleep.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
61 citing papers in PubMed, 104 citations in OpenAlex.
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- Trial
- Repeated morphine reorganizes sleep-wake states, cortical and central medial thalamic oscillations, and network synchronization in mice.bioRxiv : the preprint server for biology · 2026Article
- Human data at odds and in confirmation of the two-process model of sleep regulation-a perspective.Npj biological timing and sleep · 2026Review
- Sleep microstructure correlates of the first-night effect: sleep spindles and slow-wave activity in healthy adults.Sleep & breathing = Schlaf & Atmung · 2026Article
- Unstable slow oscillations couple with epileptogenic fast-rhythm bistability in sleep-related epilepsy: A stereoelectroencephalographic study.Epilepsia · 2026Article
- Early microglial response to amyloid plaques drives sleep loss in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Thalamic involvement defines distinct slow-wave subtypes in NREM sleep.Communications biology · 2026Article
- Dynamic Respiration-Neural Coupling in Substantia Nigra across Sleep and Anesthesia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Brain-wide properties of slow waves across vigilance states.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Thalamic involvement defines distinct slow-wave subtypes in NREM sleep.Research square · 2025Article
- Article
- Thalamic involvement defines distinct slow-wave subtypes in NREM sleep.bioRxiv : the preprint server for biology · 2025Article
- Sedative and hypnotic effects of nuciferine: enhancing rodent sleep via serotonergic system modulation.The international journal of neuropsychopharmacology · 2025Article
- The absence of Neuroligin-1 shapes wake/sleep architecture, rhythmic and arrhythmic activities of the electrocorticogram in female mice.Molecular brain · 2025Article
- Revisiting brain gene expression changes and protein modifications tracking homeostatic sleep pressure.Npj biological timing and sleep · 2025Review
- Evoked slow oscillations and dynamic network reorganization after stroke.Brain communications · 2025Article
- Article
- Sleep deprivation leads to non-adaptive alterations in sleep microarchitecture and amyloid-β accumulation in a murine Alzheimer model.Cell reports · 2024Article
- Brainwave Patterns and Metabolic Adaptations in Rowers Crossing the Atlantic: A Case Series Pilot Study.Cureus · 2024Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sleep-wake driven changes in non-rapid-eye-movement sleep (NREM) sleep (NREMS) EEG delta (δ-)power are widely used as proxy for a sleep homeostatic process. Here, we noted frequency increases in δ-waves in sleep-deprived mice, prompting us to re-evaluate how slow-wave characteristics relate to prior sleep-wake history. We identified two classes of δ-waves; one responding to sleep deprivation with high initial power and fast, discontinuous decay during recovery sleep (δ2) and another unrelated to time-spent-awake with slow, linear decay (δ1). Reanalysis of previously published datasets demonstrates that δ-band heterogeneity after sleep deprivation is also present in human subjects. Similar to sleep deprivation, silencing of centromedial thalamus neurons boosted subsequent δ2-waves, specifically. δ2-dynamics paralleled that of temperature, muscle tone, heart rate, and neuronal ON-/OFF-state lengths, all reverting to characteristic NREMS levels within the first recovery hour. Thus, prolonged waking seems to necessitate a physiological recalibration before typical NREMS can be reinstated.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.