Evidence map›Paper›PMID 32561724›Full record

ArticleNature communications2020

Jellyfish genomes reveal distinct homeobox gene clusters and conservation of small RNA processing.

Wenyan Nong, Jianquan Cao, Yiqian Li, Zhe Qu, Jin Sun, Thomas Swale, Ho Yin Yip, Pei Yuan Qian, Jian-Wen Qiu, Hoi Shan Kwan and 9 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
23.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 90 citations in OpenAlex.

  1. Article
  2. ParaHox Genes Revisited: From Gut Patterning to Integrated Axial and Neural Organization in Rotifera.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2026
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  8. Article
  9. Review
  10. Article
  11. Article
  12. PIWI proteins and piRNAs: key regulators of stem cell biology.Frontiers in cell and developmental biology · 2025
    Review
  13. Article
  14. The genome of the colonial hydroidGenome research · 2024
    Article
  15. Jellyfish in Hong Kong: a citizen science dataset.GigaByte (Hong Kong, China) · 2024
    Article
  16. Article
  17. Article
  18. The genome of the deep-sea anemoneProceedings. Biological sciences · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 5 countries.

Wenyan Nong *School of Life Sciences, Simon F.S. Li Marine Science Laboratory, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Shatin, Hong Kong.ORCID http://orcid.org/0000-0002-3277-716X
Jianquan Cao *School of Life Sciences, Simon F.S. Li Marine Science Laboratory, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Yiqian Li *School of Life Sciences, Simon F.S. Li Marine Science Laboratory, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Zhe Qu *School of Life Sciences, Simon F.S. Li Marine Science Laboratory, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Jin SunDepartment of Ocean Science, Division of Life Science and Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong.
Thomas SwaleDovetail Genomics, Scotts Valley, CA, USA.
Ho Yin YipSchool of Life Sciences, Simon F.S. Li Marine Science Laboratory, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Pei Yuan QianDepartment of Ocean Science, Division of Life Science and Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong.ORCID http://orcid.org/0000-0003-4074-9078
Jian-Wen QiuDepartment of Biology, Hong Kong Baptist University, Kowloon Tong, Hong Kong.ORCID http://orcid.org/0000-0002-1541-9627
Hoi Shan KwanSchool of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong.
William BendenaDepartment of Biology, Queen's University, Kingston, ON, Canada.ORCID http://orcid.org/0000-0003-3874-4681
Stephen TobeDepartment of Cell and Systems Biology, University of Toronto, Toronto, ON, Canada.ORCID http://orcid.org/0000-0002-5554-0966
Ting Fung ChanSchool of Life Sciences, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Shatin, Hong Kong.ORCID http://orcid.org/0000-0002-0489-3884
Kevin Y YipDepartment of Computer Science and Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong.ORCID http://orcid.org/0000-0001-5516-9944
Ka Hou ChuSchool of Life Sciences, Simon F.S. Li Marine Laboratory, The Chinese University of Hong Kong, Shatin, Hong Kong.ORCID http://orcid.org/0000-0001-8107-5415
Sai Ming NgaiSchool of Life Sciences, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Karl Yk TsimDivision of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong.
Peter W H HollandDepartment of Zoology, University of Oxford, Oxford, OX1 3SZ, UK. peter.holland@zoo.ox.ac.uk.ORCID http://orcid.org/0000-0003-1533-9376
Jerome H L HuiSchool of Life Sciences, Simon F.S. Li Marine Science Laboratory, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Shatin, Hong Kong. jeromehui@cuhk.edu.hk.ORCID http://orcid.org/0000-0003-1355-8495
Chinese University of Hong Kong · HKHong Kong University of Science and Technology · HKDovetail Genomics (United States) · USHong Kong Baptist University · HKQueen's University · CAUniversity of Oxford · GBUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phylum Cnidaria represents a close outgroup to Bilateria and includes familiar animals including sea anemones, corals, hydroids, and jellyfish. Here we report genome sequencing and assembly for true jellyfish Sanderia malayensis and Rhopilema esculentum. The homeobox gene clusters are characterised by interdigitation of Hox, NK, and Hox-like genes revealing an alternate pathway of ANTP class gene dispersal and an intact three gene ParaHox cluster. The mitochondrial genomes are linear but, unlike in Hydra, we do not detect nuclear copies, suggesting that linear plastid genomes are not necessarily prone to integration. Genes for sesquiterpenoid hormone production, typical for arthropods, are also now found in cnidarians. Somatic and germline cells both express piwi-interacting RNAs in jellyfish revealing a conserved cnidarian feature, and evidence for tissue-specific microRNA arm switching as found in Bilateria is detected. Jellyfish genomes reveal a mosaic of conserved and divergent genomic characters evolved from a shared ancestral genetic architecture.

Indexed as

Genes, HomeoboxMultigene FamilyAnimalsDevelopmental BiologyGenomeGenome, MitochondrialHormonesMicroRNAsMitochondriaPhylogenyPlastidsRNARNA, Small InterferingScyphozoaSequence Analysis, DNASpecies SpecificityHormonesMicroRNAsRNARNA, Small Interfering

Identifiers

PMID32561724
PMCPMC7305137
OpenAlexW3036185121

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.