Evidence map›Paper›PMID 32561707›Full record

ArticleTranslational psychiatry2020

Linking depressive symptom dimensions to cerebellar subregion volumes in later life.

Hannah R Bogoian, Tricia Z King, Jessica A Turner, Eric S Semmel, Vonetta M Dotson

Abstract read
In one paragraph

Article in Translational psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Consensus Paper: Cerebellum and Ageing.Cerebellum (London, England) · 2024
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hannah R BogoianDepartment of Psychology, Georgia State University, Atlanta, GA, USA.
Tricia Z KingDepartment of Psychology, Georgia State University, Atlanta, GA, USA.ORCID http://orcid.org/0000-0003-1363-9914
Jessica A TurnerDepartment of Psychology, Georgia State University, Atlanta, GA, USA.ORCID http://orcid.org/0000-0003-0076-8434
Eric S SemmelDepartment of Psychology, Georgia State University, Atlanta, GA, USA.ORCID http://orcid.org/0000-0001-6996-5335
Vonetta M DotsonDepartment of Psychology, Georgia State University, Atlanta, GA, USA. vdotson1@gsu.edu.ORCID http://orcid.org/0000-0002-3043-3320

Funding

Dissociating Components of Anhedonia: Pilot Behavioral and fMRI Data for the Effort Expenditure for Rewards TaskR03MH109336 · NIMH · UNIVERSITY OF FLORIDA · PI BOWERS, DAWN · 2015 to 2016
$150k
National Science Foundation (NSF) Cooperative Agreement No. DMR-1157490NIMH NIH HHS R03 MH109336U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) R03 MH109336-02
6 · The paper itself

Abstract

The present study examined the relationship between subthreshold depressive symptoms and gray matter volume in subregions of the posterior cerebellum. Structural magnetic resonance imaging data from 38 adults aged 51 to 80 years were analyzed along with participants' responses to the Center for Epidemiologic Studies Depression Scale. Subscale scores for depressed mood, somatic symptoms, and lack of positive affect were calculated, and multiple regression analyses were used to examine the relationship between symptom dimensions and cerebellar volumes. Greater total depressive symptoms and greater somatic symptoms of depression were significantly related to larger volumes of vermis VI, a region within the salience network, which is altered in depression. Exploratory analyses revealed that higher scores on the lack of positive affect subscale were related to larger vermis VIII volumes. These results support that depressive symptom profiles have unique relationships within the cerebellum that may be important as the field move towards targeted treatment approaches for depression.

Indexed as

DepressionGray MatterAdultCerebellumCerebral CortexHumansMagnetic Resonance Imaging

Identifiers

PMID32561707
PMCPMC7305200

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.