Evidence map›Paper›PMID 32561655›Full record

ArticleMolecular cancer research : MCR2020

Proteasome Subunits Differentially Control Myeloma Cell Viability and Proteasome Inhibitor Sensitivity.

Chang-Xin Shi, Yuan Xiao Zhu, Laura A Bruins, Cecilia Bonolo de Campos, William Stewart, Esteban Braggio, A Keith Stewart

Open access · greenAbstract read
In one paragraph

Article in Molecular cancer research : MCR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Chang-Xin ShiDepartment of Hematology, Mayo Clinic in Arizona, Scottsdale, Arizona.
Yuan Xiao ZhuDepartment of Hematology, Mayo Clinic in Arizona, Scottsdale, Arizona.
Laura A BruinsDepartment of Hematology, Mayo Clinic in Arizona, Scottsdale, Arizona.
Cecilia Bonolo de CamposDepartment of Hematology, Mayo Clinic in Arizona, Scottsdale, Arizona.
William StewartDepartment of Hematology, Mayo Clinic in Arizona, Scottsdale, Arizona.
Esteban BraggioDepartment of Hematology, Mayo Clinic in Arizona, Scottsdale, Arizona.
A Keith StewartDepartment of Hematology, Mayo Clinic in Arizona, Scottsdale, Arizona. stewart.keith@mayo.edu.
Mayo Clinic in Arizona · USMayo Clinic · US

Funding

Project 4: Targeting Resistance to T-Cell Directed Therapy in Multiple MyelomaP50CA186781 · NCI · MAYO CLINIC ARIZONA · PI Rafael Fonseca · 2015 to 2026
$25.5M
Project 3 - Modeling Proteasome Inhibitor Response and Resistance in Cell Lines and Patient Samples with Single Cell Analysis of SubpopulationsU54CA224018 · NCI · MAYO CLINIC ARIZONA · PI BERGSAGEL, PETER LEIF · 2017 to 2021
$6.0M
Omega-3 fatty acids to reduce risk for breast cancerR01CA114018 · NCI · MARSHALL UNIVERSITY · PI HARDMAN, WANDA ELAINE · 2007 to 2010
$1.2M
NCI NIH HHS P50 CA186781NCI NIH HHS R01 CA114018NCI NIH HHS U54 CA224018
6 · The paper itself

Abstract

We generated eight multiple myeloma cell lines resistant to bortezomib; five acquired

Indexed as

Cell DifferentiationCell SurvivalHumansMultiple MyelomaProteasome InhibitorsProteasome Inhibitors

Identifiers

PMID32561655
PMCPMC7541608
OpenAlexW3036072512

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.