ArticleApplied and environmental microbiology2020
Microampere Electric Current Causes Bacterial Membrane Damage and Two-Way Leakage in a Short Period of Time.
Article in Applied and environmental microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 60 citations in OpenAlex.
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- Electrofermentation increases concentration of poly γ-glutamic acid in Bacillus subtilis biofilms.Microbial biotechnology · 2024Article
- An Effective Sanitizer for Fresh Produce Production:Microbiology spectrum · 2023Article
- Green fabrication of chitosan nanoparticles using Lavendula angustifolia, optimization, characterization and in‑vitro antibiofilm activity.Scientific reports · 2023Article
- Direct Identification of Label-Free Gram-Negative Bacteria with Bioreceptor-Free Concentric Interdigitated Electrodes.Biosensors · 2023Article
- Nanostructured Conductive Polypyrrole for Antibacterial Components in Flexible Wearable Devices.Research (Washington, D.C.) · 2023Article
- Cationic Covalent Organic Polymer Thin Film for Label-free Electrochemical Bacterial Cell Detection.ACS sensors · 2022Article
- Review
- Effect of Low Amperage Electric Current on Staphylococcus Aureus-Strategy for Combating Bacterial Biofilms Formation on Dental Implants in Cystic Fibrosis Patients, In Vitro Study.Materials (Basel, Switzerland) · 2021Article
- Pulse Voltage Electrical Stimulation for Bacterial Inactivation and Wound Healing in Mice with Diabetes.Avicenna journal of medical biotechnologyArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Physical agents, such as low electric voltage and current, have recently gained attention for antimicrobial treatment due to their bactericidal capability. Although microampere electric current was shown to suppress the growth of bacteria, it remains unclear to what extent the microampere current damaged the bacterial membrane. Here, we investigated the membrane damage and two-way leakage caused by microampere electric current (≤100 μA) with a short exposure time (30 min). Based on MitoTracker staining, propidium iodide staining, filtration assays, and quantitative single-molecule localization microscopy, we observed significant membrane damage, which allowed two-way leakage of ions, small molecules, and proteins. This study paves the way to new development of antimicrobial applications for ultralow electric voltage and current.
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