Evidence map›Paper›PMID 32561497›Full record

ArticleThe journal of allergy and clinical immunology. In practice2020

Impact of COVID-19 on Pediatric Asthma: Practice Adjustments and Disease Burden.

Nikolaos G Papadopoulos, Adnan Custovic, Antoine Deschildre, Alexander G Mathioudakis, Wanda Phipatanakul, Gary Wong, Paraskevi Xepapadaki, Ioana Agache, Leonard Bacharier, Matteo Bonini and 36 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05220488 (Fear of COVID-19 and Physical Activity Level of Children With Asthma), which is not on this map. Cited by 90 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 4 pooled it
18.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05220488 completednot on this mapstarted 2022, after this paper: background citation

Fear of COVID-19 and Physical Activity Level of Children With Asthma

TypeobservationalSponsorBartın UnıversityRan2022 to 2022Enrolled80ConditionsAsthma in ChildrenArmsAssessment
3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 4 syntheses or guidelines pooled it, 165 citations in OpenAlex.

  1. Prevalence of respiratory viruses in stable and acute asthma: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Home-based educational interventions for children with asthma.The Cochrane database of systematic reviews · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Changes in caregiver mental health and pediatric asthma control during COVID-19.The Journal of asthma : official journal of the Association for the Care of Asthma · 2023
    Trial
  6. Asthma control and exacerbation risk following SARS-CoV-2 infection in the post-acute COVID-19 phase: a systematic review.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2026
    Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Article
  13. Tele-Monitoring Applications in Respiratory Allergy.Journal of clinical medicine · 2024
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Reduced asthma morbidity during COVID-19 in minority children: is medication adherence a reason?The Journal of asthma : official journal of the Association for the Care of Asthma · 2023
    Article

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

46 authors at 20 institutions in 26 countries.

Nikolaos G PapadopoulosDivision of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester, United Kingdom; Allergy Department, 2nd Paediatric Clinic, National and Kapodistrian University of Athens, Athens, Greece. Electronic address: ngpallergy@gmail.com.
Adnan CustovicDepartment of Paediatrics, Imperial College London, London, United Kingdom.
Antoine DeschildrePediatric Pulmonology and Allergy Department, Hôpital Jeanne de Flandre, Lille, France.
Alexander G MathioudakisDivision of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester, United Kingdom; North West Lung Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Wanda PhipatanakulChildren's Hospital Boston, Pediatric Allergy and Immunology, Boston, Mass.
Gary WongDepartment of Pediatrics, Faculty of Medicine, The Chinese University of Hong Kong, Sha Tin, Hong Kong.
Paraskevi XepapadakiAllergy Department, 2nd Paediatric Clinic, National and Kapodistrian University of Athens, Athens, Greece.
Ioana AgacheAllergy & Clinical Immunology, Transylvania University, Brasov, Romania.
Leonard BacharierDivision of Allergy, Immunology and Pulmonary Medicine, Department of Pediatrics, Washington University, St Louis, Mo.
Matteo BoniniDepartment of Cardiovascular and Thoracic Sciences, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli - IRCCS, Rome, Italy; National Heart and Lung Institute (NHLI), Imperial College London, London, United Kingdom.
Jose A Castro-RodriguezDivision of Pediatrics, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile.
Zhimin ChenPulmonology Department, Children's Hospital Zhejiang University School of Medicine, Zhejiang, China.
Timothy CraigDepartment of Allergy and Immunology, Penn State University, State College, Pa.
Francine M DucharmeDepartment of Pediatrics, University of Montréal, Department of Social and Preventive Medicine, University of Montréal, Montréal, QC, Canada.
Zeinab Awad El-SayedPediatric Allergy and Immunology Unit, Children's Hospital, Ain Shams University, Cairo, Egypt.
Wojciech FeleszkoDepartment of Pediatric Respiratory Diseases and Allergy, The Medical University of Warsaw, Warsaw, Poland.
Alessandro FiocchiAllergy Department, Bambino Gesù Children's Hospital, Rome, Italy.
Luis Garcia-MarcosPediatric Respiratory and Allergy Units, "Virgen de la Arrixaca" Children's University Clinical Hospital, University of Murcia, Murcia, Spain; Institute for Biomedical Research of Murcia, IMIB-Arrixaca, & Network of Asthma and Adverse and Allergic Reactions (ARADyAL), Murcia, Spain.
James E GernDepartment of Pediatrics and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis.
Anne GohDepartment of Internal Medicine, Rush Medical College, Chicago, Ill.
René Maximiliano GómezResearch & Education, Ayre Foundation, Salta, Argentina; Allergy & Asthma Department, Alas Medical Institute, Salta, Argentina.
Eckard H HamelmannChildren's Center Bethel, EvKB, University Bielefeld, Bielefeld, Germany.
Gunilla HedlinPaediatric Allergy, Centre for Allergy Research, Karolinska Institutet, Solna, Sweden.
Elham M HossnyPediatric Allergy and Immunology Unit, Children's Hospital, Ain Shams University, Cairo, Egypt.
Tuomas JarttiDepartment of Pediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, Finland.
Omer KalayciPediatric Allergy and Asthma Unit, Hacettepe University School of Medicine, Ankara, Turkey.
Alan KaplanFamily Physician Airways Group of Canada, Edmonton, AB, Canada.
Jon KonradsenAstrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Piotr KunaDepartment of Internal Medicine, Asthma and Allergy, Medical University of Lodz, Lodz, Poland.
Susanne LauCharité Universitätsmedizin Berlin, Pediatric Pulmonology, Immunology and Intensive Care Medicine, Berlin, Germany.
Peter Le SouefSchool of Paediatrics & Child Health, Faculty of Medicine, Dentistry and Health Sciences, University of Western Australia, Crawley, WA, Australia.
Robert F LemanskeDepartments of Pediatrics and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis.
Mika J MäkeläDepartment of Allergy, Helsinki University Central Hospital, Helsinki, Finland.
Mário Morais-AlmeidaAllergy Center, CUF Descobertas Hospital, Lisbon, Portugal.
Clare MurrayDivision of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester, United Kingdom.
Karthik NagarajuVN Allergy & Asthma Research Centre, Chennai, Tamilnadu, India.
Leyla Namazova-BaranovaPediatric Department, Pirogov Russian National Research Medical University, the Ministry of Health, Moscow, Russia.
Antonio Nieto GarciaPediatric Pulmonology & Allergy Unit, Children's Hospital la Fe, Valencia, Spain.
Osman M YusufAllergy and Respiratory Research Group, Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Paulo M C PitrezPediatric Pulmonology Division, Hospital Moinhos de Vento, Porto Alegre, Brazil.
Petr PohunekPediatric Pulmonology, Pediatric Department, 2nd Faculty of Medicine, Charles University, Prague, University Hospital Motol, Prague, Czech Republic.
Cesar Fireth Pozo BeltránTeaching and Research Department and Paediatric Allergy Department, Hospital with Specialties Juan María de Salvatierra, La Paz, Baja California Sur México, La Paz, Mexico; Allergy & Immunology Department, Hospital Infantil de Medico Federico Gomez, Mexico City, Mexico.
Graham C RobertsPaediatric Allergy and Respiratory Medicine within Medicine at the University of Southampton, Southampton, United Kingdom.
Arunas ValiulisClinic of Children's Diseases, Institute of Clinical Medicine, Medical Faculty of Vilnius University, Vilnius, Lithuania.
Heather J ZarDepartment of Pediatrics & Child Health, MRC Unit on Child & Adolescent Health, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa.
Pediatric Asthma in Real Life Collaborators
Ain Shams University Hospital · EGBoehringer Ingelheim (India) · INSanofi (France) · FRAstraZeneca (Brazil) · BRBoehringer Ingelheim (China) · CNBoehringer Ingelheim (Egypt) · EGImperial College London · GBKarolinska Institutet · SEMenarini Group (Italy) · ITNational and Kapodistrian University of Athens · GRPhilips (United Kingdom) · GBUniversity of Manchester · GBUniversity of Wisconsin–Madison · USAstraZeneca (France) · FRBambino Gesù Children's Hospital · ITBenemerito Hospital General con Especialidades "Juan Maria de Salvatierra" · MXBoston Children's Hospital · USCharité - Universitätsmedizin Berlin · DECharles University · CZChildren's Hospital of Zhejiang University · CN

Funding

Medical Research Council MR/K002449/1Medical Research Council MR/K002449/2
6 · The paper itself

Abstract

backgroundIt is unclear whether asthma may affect susceptibility or severity of coronavirus disease 2019 (COVID-19) in children and how pediatric asthma services worldwide have responded to the pandemic.

objectiveTo describe the impact of the COVID-19 pandemic on pediatric asthma services and on disease burden in their patients.

methodsAn online survey was sent to members of the Pediatric Asthma in Real Life think tank and the World Allergy Organization Pediatric Asthma Committee. It included questions on service provision, disease burden, and the clinical course of confirmed cases of COVID-19 infection among children with asthma.

resultsNinety-one respondents, caring for an estimated population of more than 133,000 children with asthma, completed the survey. COVID-19 significantly impacted pediatric asthma services: 39% ceased physical appointments, 47% stopped accepting new patients, and 75% limited patients' visits. Consultations were almost halved to a median of 20 (interquartile range, 10-25) patients per week. Virtual clinics and helplines were launched in most centers. Better than expected disease control was reported in 20% (10%-40%) of patients, whereas control was negatively affected in only 10% (7.5%-12.5%). Adherence also appeared to increase. Only 15 confirmed cases of COVID-19 were reported among the population; the estimated incidence is not apparently different from the reports of general pediatric cohorts.

conclusionsChildren with asthma do not appear to be disproportionately affected by COVID-19. Outcomes may even have improved, possibly through increased adherence and/or reduced exposures. Clinical services have rapidly responded to the pandemic by limiting and replacing physical appointments with virtual encounters.

Indexed as

Appointments and SchedulesAsthmaBetacoronavirusChildCoronavirus InfectionsCOVID-19Global HealthHumansMedication AdherencePandemicsPneumonia, ViralSARS-CoV-2Severity of Illness IndexTelemedicineTime FactorsAdherenceAsthmaChildrenControlCOVID-19SARS-CoV2Virus

Identifiers

PMID32561497
PMCPMC7297686
OpenAlexW3034678323

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.