Evidence map›Paper›PMID 32561467›Full record

ArticleContemporary clinical trials2020

A randomized comparison trial of culturally adapted HIV prevention approaches for Native Americans reducing trauma symptoms versus substance misuse: The Healing Seasons protocol.

C R Pearson, D Kaysen, D Huh, M Bedard-Gillgan, D Walker, R Marin, K Saluskin

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03112369 (Preventing HIV Among Native Americans Through the Treatment PTSD & Substance Use), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03112369 nacompletednot on this map

Preventing HIV Among Native Americans Through the Treatment PTSD & Substance Use

TypeinterventionalSponsorUniversity of WashingtonRan2017 to 2024Enrolled125ConditionsHIV Prevention, PTSD and Substance Use DisorderArmsNarrative Exposure Therapy (NET), Motivational Interviewing w/Skills Training (MIST)
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

C R PearsonIndigenous Wellness Research Institute, School of Social Work, University of Washington, Seattle, WA, USA. Electronic address: pearsonc@uw.edu.
D KaysenDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA.
D HuhIndigenous Wellness Research Institute, School of Social Work, University of Washington, Seattle, WA, USA.
M Bedard-GillganDepartment of Psychiatry, University of Washington, Seattle, WA, USA.
D WalkerInnovative Programs Research Group, School of Social Work, University of Washington, Seattle, WA, USA.
R MarinIndigenous Wellness Research Institute, School of Social Work, University of Washington, Seattle, WA, USA.
K SaluskinYakama Nation Behavioral Health Services, Toppenish, WA, USA.
University of Washington · USBehavioral Health Services · USStanford University · US

Funding

Preventing HIV among Native Americans through the treatment PTSD & substance useR01MD011574 · NIMHD · UNIVERSITY OF WASHINGTON · PI KAYSEN, DEBRA L, PEARSON, CYNTHIA RENEE · 2016 to 2020
$3.3M
Cognitive Processing Intervention for HIV/STI and Substance Use among Native WomeR34DA034529 · NIDA · UNIVERSITY OF WASHINGTON · PI PEARSON, CYNTHIA RENEE · 2012 to 2014
$645k
NIDA NIH HHS R34 DA034529NIMHD NIH HHS R01 MD011574
6 · The paper itself

Abstract

Native Americans (NA) experience interrelated risks of trauma exposure, substance use, and HIV risk behaviors that put them at increased risk for HIV infection. Despite these known risk factors, there are very few published randomized trials testing interventions to reduce trauma-related symptoms and substance misuse among NA.

methodsThe Healing Seasons study is a randomized comparsion trial of two counseling strategies, Narrative Exposure Therapy (NET) addressing PTSD or Motivational interviewing with cognitive behavioral therapy skills training (MIST) addressing substance misuse as a means to prevent HIV among NA. Using a community-based participatory research approach, we adapted both evidence-based interventions to be specific to the risk contexts and realities of NA and to include psychoeducational and skill-building components that include cultural-specific stories, virtues, and traditional treatment strategies. Participants, 16 years and older, were recruited from a Pacific Northwest tribal community, screened over the phone, enrolled in person, and randomized in equal numbers to NET or MIST. We stratified by age (16-29 years and 30 or older) and gender (male or female identified) to ensure balance between treatment arms. The primary outcomes were number of sex partners and frequency of sexual acts (with and without condoms), sex under the influence of substances, frequency of substance use, and PTSD severity. DISCUSSION: Behavioral interventions for NA are needed to prevent HIV risk behaviors when faced with trauma symptoms and substance misuse. This study will provide evidence to determine feasibility and efficacy of addressing related risk factors as part of counseling-based HIV prevention intervention to reduce sexual risk among this population.

trial registrationClinicalTrials.gov number, NCT03112369, registered April 12, 2017.

Indexed as

HIV InfectionsSubstance-Related DisordersAmerican Indian or Alaska NativeFemaleHumansInfant, NewbornMaleSeasonsSexual BehaviorHIVNarrative Exposure TherapyNative AmericansPTSDSubstance useTrauma

Identifiers

PMID32561467
PMCPMC8893012
OpenAlexW3035969526

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.