Evidence map›Paper›PMID 32561373›Full record

SynthesisJournal of the American Academy of Dermatology2021

Psychosocial and psychiatric comorbidities and health-related quality of life in alopecia areata: A systematic review.

Atrin Toussi, Virginia R Barton, Stephanie T Le, Oma N Agbai, Maija Kiuru

2 registry-linked trialsOpen access · greenAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of the American Academy of Dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 103 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 4 pooled it
16.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06399783 phase4not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Topical Simvastatin Versus Topical Steroid in Treatment of Alopecia Areata: Clinical, Dermoscopic and Immunohistochemical Study

TypeinterventionalSponsorAssiut UniversityRan2024 to 2027Enrolled54ConditionsAlopecia AreataArmsSimvastatin, Mometasone Furoate, Fractional CO2 laser
NCT06802705 completednot on this mapstarted 2023, after this paper: background citation

The Impact of Psychosocial Stress on Quality of Life in Saudi Arabian Patients With Alopecia Areata

TypeobservationalSponsorUniversity of JeddahRan2023 to 2024Enrolled398ConditionsAlopecia AreataArmsPsychosocial Stress on Quality of Life
3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 4 syntheses or guidelines pooled it, 191 citations in OpenAlex.

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43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Atrin ToussiDepartment of Dermatology, University of California, Davis, Sacramento, California; School of Medicine, University of California, Davis, Sacramento, California.
Virginia R BartonDepartment of Dermatology, University of California, Davis, Sacramento, California.
Stephanie T LeDepartment of Dermatology, University of California, Davis, Sacramento, California.
Oma N AgbaiDepartment of Dermatology, University of California, Davis, Sacramento, California.
Maija KiuruDepartment of Dermatology, University of California, Davis, Sacramento, California; Department of Pathology and Laboratory Medicine, University of California, Davis, Sacramento, California. Electronic address: mkiuru@ucdavis.edu.
University of California, Davis · US

Funding

Molecular basis of melanocytic neviK23AR074530 · NIAMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KIURU, MAIJA HELENA TUULIA · 2019 to 2023
$840k
NIAMS NIH HHS K23 AR074530
6 · The paper itself

Abstract

backgroundAlopecia areata (AA) is an immune-mediated disease resulting in nonscarring hair loss. Systematic reviews on the psychosocial and psychiatric comorbidities, health-related quality of life, and interventions targeting psychosocial well-being are limited.

objectiveTo conduct a systematic review of the psychosocial comorbidities, health-related quality of life, and treatment options targeting psychosocial well-being in adult and pediatric AA patients.

methodsA systematic review was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines within the PubMed database. Specific search terms included, but were not limited to, alopecia areata, psychosocial, psychiatry, and quality of life. Studies were then evaluated for their design and categorized into corresponding levels of evidence according to the guidelines adapted from the Oxford Center for Evidence Based Medicine.

findingsSeventy-three reports met inclusion criteria, involving approximately 414,319 unique participants. AA patients were found to have psychiatric comorbidities, particularly anxiety and depression. Health-related quality of life is reduced in AA patients, but data on pediatric AA quality of life are limited. Psychotherapy is often recommended as adjuvant treatment.

conclusionAA has substantial psychosocial impact on patients and results in reduced health-related quality of life. Addressing this should be an active part of treatment.

Indexed as

Alopecia AreataAnxietyChildChild Behavior DisordersComorbidityDepressionHumansMental DisordersQuality of LifeSuicidealopecia areataanxietydepressionhypnosispersonalitypsychiatrypsychosocialquality of lifewigs

Identifiers

PMID32561373
PMCPMC8260215
OpenAlexW3034958681

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.