Evidence map›Paper›PMID 32561221›Full record

ArticleBrain, behavior, and immunity2020

Psychosocial factors and hospitalisations for COVID-19: Prospective cohort study based on a community sample.

G D Batty, I J Deary, M Luciano, D M Altschul, M Kivimäki, C R Gale

Open access · hybridAbstract read
In one paragraph

Article in Brain, behavior, and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
9.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 1 synthesis or guideline pooled it, 130 citations in OpenAlex.

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  19. Evaluation of Depression and Anxiety in Rheumatoid Arthritis Patients During COVID-19 Pandemic.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2023
    Article
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

G D BattyDepartment of Epidemiology and Public Health, University College London, UK. Electronic address: david.batty@ucl.ac.uk.
I J DearyLothian Birth Cohorts, Department of Psychology, University of Edinburgh, UK. Electronic address: ian.deary@ed.ac.uk.
M LucianoDepartment of Psychology, The University of Edinburgh, Edinburgh, UK. Electronic address: michelle.luciano@ed.ac.uk.
D M AltschulDepartment of Psychology, The University of Edinburgh, Edinburgh, UK. Electronic address: drew.altschul@ed.ac.uk.
M KivimäkiDepartment of Epidemiology and Public Health, University College London, UK. Electronic address: m.kivimaki@ucl.ac.uk.
C R GaleLothian Birth Cohorts, Department of Psychology, University of Edinburgh, UK; MRC Lifecourse Epidemiology Unit, University of Southampton, UK. Electronic address: crg@mrc.soton.ac.uk.
NHS Lothian · GBPublic Health England · GBUniversity of Edinburgh · GB

Funding

Education, socioeconomic status and Aging: transitions from multimorbidity to functional limitations and mortalityR01AG056477 · NIA · UNIVERSITY COLLEGE LONDON · PI KIVIMAKI, MIKA J, SINGH-MANOUX, ARCHANA · 2018 to 2022
$2.8M
Evaluating Longitudinal Changes in the Human Structural Connectome in Relation to Cognitive AgingR01AG054628 · NIA · UNIVERSITY OF TEXAS AT AUSTIN · PI TUCKER-DROB, ELLIOT MAX · 2017 to 2021
$2.7M
Healthy transitions from mid-life to early older age: biomedical follow-up of 1958 Birth Cohort Study members at age 60R01AG052519 · NIA · UNIVERSITY COLLEGE LONDON · PI BATTY, DAVID, GOODMAN, ALISSA · 2017 to 2021
$1.9M
Healthy transitions from mid-life to early older age: biomedical follow-up of 1958 Birth Cohort Study members at age 60R56AG052519 · NIA · UNIVERSITY COLLEGE LONDON · PI BATTY, DAVID, GOODMAN, ALISSA · 2016 to 2016
$500k
Medical Research Council G0700704Medical Research Council MR/P023444/1Medical Research Council MR/R024227/1NIA NIH HHS R01 AG052519NIA NIH HHS R01 AG054628NIA NIH HHS R01 AG056477NIA NIH HHS R56 AG052519
6 · The paper itself

Abstract

backgroundWhile certain infectious diseases have been linked to socioeconomic disadvantage, mental health problems, and lower cognitive function, relationships with COVID-19 are either uncertain or untested. Our objective was to examine the association of a range of psychosocial factors with hospitalisation for COVID-19.

methodsUK Biobank, a prospective cohort study, comprises around half a million people who were aged 40-69 years at study induction between 2006 and 2010 when information on psychosocial factors and covariates were captured. Hospitalisations for COVID-19 were ascertained between 16th March and 26th April 2020.

resultsThere were 908 hospitalisations for COVID-19 in an analytical sample of 431,051 England-based study members. In age- and sex-adjusted analyses, an elevated risk of COVID-19 was related to disadvantaged levels of education (odds ratio; 95% confidence interval: 2.05; 1.70, 2.47), income (2.00; 1.63, 2,47), area deprivation (2.20; 1.86, 2.59), occupation (1.39; 1.14, 1.69), psychological distress (1.58; 1.32, 1.89), mental health (1.50; 1.25, 1.79), neuroticism (1.19; 1.00, 1.42), and performance on two tests of cognitive function - verbal and numerical reasoning (2.66; 2.06, 3.34) and reaction speed (1.27; 1.08, 1.51). These associations were graded (p-value for trend ≤ 0.038) such that effects were apparent across the full psychosocial continua. After mutual adjustment for these characteristics plus ethnicity, comorbidity, and lifestyle factors, only the relationship between lower cognitive function as measured using the reasoning test and risk of the infection remained (1.98; 1.38, 2.85).

conclusionsA range of psychosocial factors revealed associations with hospitalisation for COVID-19 of which the relation with cognitive function, a marker of health literacy, was most robust.

Indexed as

CognitionAdultAgedBetacoronavirusCohort StudiesCoronavirus InfectionsCOVID-19Educational StatusFemaleHospitalizationHumansIncomeMaleMental HealthMiddle AgedNeuroticismCohort studyCOVID-19HospitalisationRisk factorsUK Biobank

Identifiers

PMID32561221
PMCPMC7297693
OpenAlexW3035494333

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.