Evidence map›Paper›PMID 32560684›Full record

ArticleBMC veterinary research2020

Impact of dietary Mannan-oligosaccharide and β-Glucan supplementation on growth, histopathology, E-coli colonization and hepatic transcripts of TNF-α and NF- ϰB of broiler challenged with E. coli O

Sabreen Ezzat Fadl, Ghada Ahmed El-Gammal, Osama Atia Sakr, Aly A B S Salah, Ayman Ali Atia, Abdelbary Mohammed Prince, Abdelhaleem Mohamed Hegazy

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

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  9. Survivability ofJournal of advanced veterinary and animal research · 2023
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  17. Impact of Dietary or Drinking WaterFrontiers in veterinary science · 2021
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sabreen Ezzat FadlBiochemistry Department, Faculty of Veterinary Medicine - Matrouh University, Matrouh, Egypt. nourmallak@yahoo.com.ORCID https://orcid.org/0000-0001-5541-6159
Ghada Ahmed El-GammalMicrobiology Unit, Animal Health Res. Inst. (ARC), Kafrelsheikh, Egypt.
Osama Atia SakrBiochemistry, Nutritional Deficiency Diseases and Toxicology Unit, Animal Health Res. Inst. (ARC), kafrelsheikh, Egypt.
Aly A B S SalahPharmacology Unit, Animal Health Res. Inst. (ARC), Kafrelsheikh, Egypt.
Ayman Ali AtiaPathology Unit, Animal Health Res. Inst. (ARC), Kafrelsheikh, Egypt.
Abdelbary Mohammed PrinceDepartment of Molecular Biology, Faculty of Vet. Med., Cairo University, Cairo, Egypt.
Abdelhaleem Mohamed HegazyPoultry diseases Unit, Animal Health Res. Inst. (ARC), Kafrelsheikh, Egypt.
Cairo University · EGEgypt Nanotechnology Center · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUsing probiotics have become popular. They are considered an alternative to Antibiotic Growth Promoters (AGP). Probiotics are supplemented into animal feed for improving growth performance along with preventing and controlling enteric pathogens. The aim of this work was to study the impact of dietary supplementation of Mannan-oligosaccharide and β-Glucan (Agrimos®) on broiler challenged with Escherichia coli O

resultsResults indicated significant alteration of growth performance, serum biochemistry, and selected liver gene expression with pathological lesions, especially in the lymphoid organs due to E. coli infection. These alterations were mitigated by Mannan-oligosaccharide and β-Glucan supplementation.

conclusionIt could be concluded, Mannan-oligosaccharide and β-Glucan supplementation in broiler's diet improved the immune response of broilers and mitigated pathological lesion resulted from E. coli infection.

Indexed as

Animal FeedAnimalsbeta-GlucansChickensDietEscherichia coliEscherichia coli InfectionsFemaleLiverMaleMannansNF-kappa BPoultry DiseasesProbioticsTumor Necrosis Factor-alphabeta-GlucansMannansNF-kappa BTumor Necrosis Factor-alphaAgrimosAntioxidantGene expressionGrowth performanceHistopathologyImmunostimulant

Identifiers

PMID32560684
PMCPMC7304200
OpenAlexW3036782055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.