Evidence map›Paper›PMID 32560633›Full record

ArticleBMC pediatrics2020

Does time taken by paediatric critical care transport teams to reach the bedside of critically ill children affect survival? A retrospective cohort study from England and Wales.

Sarah E Seaton, Padmanabhan Ramnarayan, Patrick Davies, Emma Hudson, Stephen Morris, Christina Pagel, Fatemah Rajah, Jo Wray, Elizabeth S Draper, DEPICT Study Team

Registry-linked trialAbstract read
In one paragraph

Article in BMC pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03520192 (Critically Ill Children and Young People), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03520192 completednot on this map

Critically Ill Children and Young People: do National Differences in

TypeobservationalSponsorGreat Ormond Street Hospital for Children NHS Foundation TrustRan2019 to 2021Enrolled2,838ConditionsAccess and Transport to Paediatric Intensive Care
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sarah E SeatonDepartment of Health Sciences, University of Leicester, University Road, Leicester, UK.
Padmanabhan RamnarayanChildren's Acute Transport Service (CATS), Great Ormond Street Hospital NHS Foundation Trust, London, UK.
Patrick DaviesNottingham University Hospital NHS Trust, Nottingham, UK.
Emma HudsonDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Stephen MorrisDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Christina PagelClinical Operational Research Unit, University College London, London, UK.
Fatemah RajahYorkshire and Humber Infant and Children's Transport Service (Embrace), Barnsley, UK.
Jo WrayHeart and Lung Directorate, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Elizabeth S DraperDepartment of Health Sciences, University of Leicester, University Road, Leicester, UK. msn@le.ac.uk.
DEPICT Study Team

Funding

Department of Health 15/136/45Health Services Research Programme 15/136/45
6 · The paper itself

Abstract

backgroundReaching the bedside of a critically ill child within three hours of agreeing the child requires intensive care is a key target for Paediatric Critical Care Transport teams (PCCTs) to achieve in the United Kingdom. Whilst timely access to specialist care is necessary for these children, it is unknown to what extent time taken for the PCCT to arrive at the bedside affects clinical outcome.

methodsData from transports of critically ill children who were admitted to Paediatric Intensive Care Units (PICUs) in England and Wales from 1 January 2014 to 31 December 2016 were extracted from the Paediatric Intensive Care Audit Network (PICANet) and linked with adult critical care data and Office for National Statistics mortality data. Logistic regression models, adjusted for pre-specified confounders, were fitted to investigate the impact of time-to-bedside on mortality within 30 days of admission and other key time points. Negative binomial models were used to investigate the impact of time-to-bedside on PICU length of stay and duration of invasive ventilation.

resultsThere were 9116 children transported during the study period, and 645 (7.1%) died within 30 days of PICU admission. There was no evidence that 30-day mortality changed as time-to-bedside increased. A similar relationship was seen for mortality at other pre-selected time points. In children who waited longer for a team to arrive, there was limited evidence of a small increase in PICU length of stay (expected number of days increased from: 7.17 to 7.58).

conclusionThere is no evidence that reducing the time-to-bedside target for PCCTs will improve the survival of critically ill children. A shorter time to bedside may be associated with a small reduction in PICU length of stay.

Indexed as

Critical IllnessIntensive Care Units, PediatricChildCritical CareEnglandHumansInfantRetrospective StudiesUnited KingdomWalesCritical care transportPaediatric intensive carePaediatric transport

Identifiers

PMID32560633
PMCPMC7304220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.