Evidence map›Paper›PMID 32560571›Full record

ReviewInternational journal of molecular sciences2020

Telocytes in the Normal and Pathological Peripheral Nervous System.

Lucio Díaz-Flores, Ricardo Gutiérrez, Mª Pino García, Sara Gayoso, Emma Gutiérrez, Lucio Díaz-Flores, José Luis Carrasco

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
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  14. Review
  15. Article
  16. Article
  17. Article
  18. Behavior and Functional Roles of CD34International journal of molecular sciences · 2022
    Review
  19. Review
  20. Telocytes: An Emerging Component of Stem Cell Niche Microenvironment.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lucio Díaz-FloresDepartment of Basic Medical Sciences, Faculty of Medicine, University of La Laguna, 38071 Tenerife, Spain.ORCID 0000-0003-1449-8738
Ricardo GutiérrezDepartment of Basic Medical Sciences, Faculty of Medicine, University of La Laguna, 38071 Tenerife, Spain.
Mª Pino GarcíaDepartment of Pathology, Eurofins® Megalab-Hospiten Hospitals, 38100 Tenerife, Spain.
Sara GayosoDepartment of Basic Medical Sciences, Faculty of Medicine, University of La Laguna, 38071 Tenerife, Spain.
Emma GutiérrezDepartment of Basic Medical Sciences, Faculty of Medicine, University of La Laguna, 38071 Tenerife, Spain.
Lucio Díaz-FloresDepartment of Basic Medical Sciences, Faculty of Medicine, University of La Laguna, 38071 Tenerife, Spain.
José Luis CarrascoDepartment of Basic Medical Sciences, Faculty of Medicine, University of La Laguna, 38071 Tenerife, Spain.
Universidad de La Laguna · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied telocytes/CD34+ stromal cells in the normal and pathological peripheral nervous system (PNS), for which we reviewed the literature and contributed our observations under light and electron microscopy in this field. We consider the following aspects: (A) general characteristics of telocytes and the terminology used for these cells (e.g., endoneurial stromal cells) in PNS; (B) the presence, characteristics and arrangement of telocytes in the normal PNS, including (i) nerve epi-perineurium and endoneurium (e.g., telopodes extending into the endoneurial space); (ii) sensory nerve endings (e.g., Meissner and Pacinian corpuscles, and neuromuscular spindles); (iii) ganglia; and (iv) the intestinal autonomic nervous system; (C) the telocytes in the pathologic PNS, encompassing (i) hyperplastic neurogenic processes (neurogenic hyperplasia of the appendix and gallbladder), highly demonstrative of telocyte characteristics and relations, (ii) PNS tumours, such as neurofibroma, schwannoma, granular cell tumour and nerve sheath myxoma, and interstitial cell of Cajal-related gastrointestinal stromal tumour (GIST), (iii) tumour-invaded nerves and (iv) traumatic, metabolic, degenerative or genetic neuropathies, in which there are fewer studies on telocytes, e.g., neuroinflammation and nerves in undescended testicles (cryptorchidism), Klinefelter syndrome, crush injury, mucopolysaccharidosis II (Hunter's syndrome) and Charcot-Marie-Tooth disease.

Indexed as

Disease SusceptibilityAnimalsBiomarkersHumansImmunohistochemistryNerve EndingsPeripheral Nervous SystemPeripheral Nervous System DiseasesTelocytesBiomarkersappendicular neurogenic hyperplasiagallbladder neurogenic hyperplasiaMeissner corpusclesnervesperipheral nervous system tumourstelocytes

Identifiers

PMID32560571
PMCPMC7352954
OpenAlexW3036840056

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.