Evidence map›Paper›PMID 32560565›Full record

ArticleBiomolecules2020

Preclinical Efficacy and Safety of an Anti-Human VEGFA and Anti-Human NRP1 Dual-Targeting Bispecific Antibody (IDB0076).

Jong-Hee Ko, Hyuk-Sang Kwon, Bomin Kim, Gihong Min, Chorong Shin, Seok-Woo Yang, Seong Wook Lee, Youngmin Lee, Dahae Hong, Yong-Sung Kim

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jong-Hee KoResearch Laboratory, ILDONG Pharmaceutical Co., Ltd., Hwaseong 18449, Korea.
Hyuk-Sang KwonResearch Laboratory, ILDONG Pharmaceutical Co., Ltd., Hwaseong 18449, Korea.
Bomin KimResearch Laboratory, ILDONG Pharmaceutical Co., Ltd., Hwaseong 18449, Korea.
Gihong MinResearch Laboratory, ILDONG Pharmaceutical Co., Ltd., Hwaseong 18449, Korea.
Chorong ShinResearch Laboratory, ILDONG Pharmaceutical Co., Ltd., Hwaseong 18449, Korea.
Seok-Woo YangResearch Laboratory, ILDONG Pharmaceutical Co., Ltd., Hwaseong 18449, Korea.
Seong Wook LeeResearch Laboratory, ILDONG Pharmaceutical Co., Ltd., Hwaseong 18449, Korea.
Youngmin LeeResearch Laboratory, ILDONG Pharmaceutical Co., Ltd., Hwaseong 18449, Korea.
Dahae HongResearch Laboratory, ILDONG Pharmaceutical Co., Ltd., Hwaseong 18449, Korea.
Yong-Sung KimDepartment of Molecular Science and Technology, Ajou University, Suwon 16499, Korea.
Daewoong Pharmaceutical (South Korea) · KRAjou University · KR

Funding

ILDONG Pharmaceutical Co., Ltd. ID13009National Research Foundation of Korea 2015M3A9D9074304
6 · The paper itself

Abstract

Although bevacizumab (Avastin

Indexed as

AnimalsAntibodies, BispecificAntineoplastic AgentsCell LineCell MovementEndothelial CellsHumansMacaca fascicularisMaleMiceMice, Inbred BALB CMice, NudeNeuropilin-1RatsRats, Sprague-DawleyVascular Endothelial Growth Factor AAntibodies, BispecificAntineoplastic AgentsNeuropilin-1NRP1 protein, humanVascular Endothelial Growth Factor AVEGFA protein, humanangiogenesisbispecific antibodyIDB0076Neuropilin-1Vascular endothelial growth factor A

Identifiers

PMID32560565
PMCPMC7356919
OpenAlexW3036096125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.