Evidence map›Paper›PMID 32560413›Full record

ArticleNutrients2020

Novel Therapeutic Approach for the Management of Mood Disorders: In Vivo and In Vitro Effect of a Combination of L-Theanine,

Vittoria Borgonetti, Paolo Governa, Marco Biagi, Nicoletta Galeotti

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Novel Combination of Choline withInternational journal of molecular sciences · 2023
    Article
  6. Dual HDAC/BRD4 Inhibitors Relieves Neuropathic Pain by Attenuating Inflammatory Response in Microglia After Spared Nerve Injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022
    Article
  7. Article
  8. Attenuation of Anxiety-Like Behavior byPharmaceuticals (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Vittoria BorgonettiDepartment of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), Section of Pharmacology, University of Florence, Viale G. Pieraccini 6, 50139 Florence, Italy.ORCID 0000-0002-2203-5285
Paolo GovernaDepartment of Biotechnology, Chemistry and Pharmacy-Department of Excellence 2018-2022, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy.ORCID 0000-0002-5976-780X
Marco BiagiDepartment of Physical Sciences, Earth and Environment, University of Siena, Strada Laterina 8, 53100 Siena, Italy.ORCID 0000-0003-2997-4178
Nicoletta GaleottiDepartment of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), Section of Pharmacology, University of Florence, Viale G. Pieraccini 6, 50139 Florence, Italy.
University of Florence · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mood disorders represent one of the most prevalent and costly psychiatric diseases worldwide. The current therapies are generally characterized by several well-known side effects which limit their prolonged use. The use of herbal medicine for the management of several psychiatric conditions is becoming more established, as it is considered a safer support to conventional pharmacotherapy. The aim of this study was to investigate the possible anxiolytic and antidepressant activity of a fixed combination of L-theanine,

Indexed as

MagnoliaMelissaAnimalsAnti-Anxiety AgentsAntidepressive AgentsBehavior, AnimalCells, CulturedDisease Models, AnimalDrug CombinationsGlutamatesMaleMiceMood DisordersPhytotherapyPlant ExtractsPlants, MedicinalAnti-Anxiety AgentsAntidepressive AgentsDrug CombinationsGlutamatesPlant ExtractstheanineanxietyCB1endocannabinoid systemexcitotoxicityflumazenilL-theaninemood disordersneuroprotection

Identifiers

PMID32560413
PMCPMC7353338
OpenAlexW3036631727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.