Evidence map›Paper›PMID 32560391›Full record

ArticleBiomedicines2020

Varespladib Inhibits the Phospholipase A

Chunfang Xie, Laura-Oana Albulescu, Kristina B M Still, Julien Slagboom, Yumei Zhao, Zhengjin Jiang, Govert W Somsen, Freek J Vonk, Nicholas R Casewell, Jeroen Kool

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 54 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Proteomic profiling and comparative hemotoxicity ofThe journal of venomous animals and toxins including tropical diseases · 2026
    Article
  8. Secreted Phospholipases A2: Drivers of Inflammation and Cancer.International journal of molecular sciences · 2024
    Review
  9. Article
  10. Article
  11. Unraveling snake venom phospholipase APharmacological reports : PR · 2023
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Toxicon: X · 2022
    Article
  18. Analysis of the Composition ofMolecules (Basel, Switzerland) · 2022
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Chunfang XieAmsterdam Institute of Molecular and Life Sciences, Division of BioAnalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.
Laura-Oana AlbulescuCentre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.
Kristina B M StillAmsterdam Institute of Molecular and Life Sciences, Division of BioAnalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.
Julien SlagboomAmsterdam Institute of Molecular and Life Sciences, Division of BioAnalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.
Yumei ZhaoInstitute of Pharmaceutical Analysis, College of Pharmacy, Jinan University, Huangpu Avenue West 601, Guangzhou 510632, China.
Zhengjin JiangInstitute of Pharmaceutical Analysis, College of Pharmacy, Jinan University, Huangpu Avenue West 601, Guangzhou 510632, China.
Govert W SomsenAmsterdam Institute of Molecular and Life Sciences, Division of BioAnalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.
Freek J VonkAmsterdam Institute of Molecular and Life Sciences, Division of BioAnalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.
Nicholas R CasewellCentre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.
Jeroen KoolAmsterdam Institute of Molecular and Life Sciences, Division of BioAnalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0002-0011-5612
Vrije Universiteit Amsterdam · NLJinan University · CNLiverpool School of Tropical Medicine · GBNaturalis Biodiversity Center · NL

Funding

China Scholarship Council (CSC) fellowship 201706250035Confidence in Concept Award CiC19017Medical Research Council MC_PC_18055Medical Research Council MR/S00016X/1Sir Henry Dale Fellowship 200517/Z/16/ZUK Medical Research Council (MRC) Research Grant MR/S00016X/1Wellcome Trust 200517/Z/16/Z
6 · The paper itself

Abstract

Phospholipase A

Indexed as

coagulopathic toxicitynanofractionationneutralizationPLA2 activityvarespladib

Identifiers

PMID32560391
PMCPMC7345350
OpenAlexW3036003840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.