Evidence map›Paper›PMID 32560363›Full record

ArticleInternational journal of environmental research and public health2020

Black-White Risk Differentials in COVID-19 (SARS-COV2) Transmission, Mortality and Case Fatality in the United States: Translational Epidemiologic Perspective and Challenges.

Laurens Holmes, Michael Enwere, Janille Williams, Benjamin Ogundele, Prachi Chavan, Tatiana Piccoli, Chinaka Chinacherem, Camillia Comeaux, Lavisha Pelaez, Osatohamwen Okundaye and 9 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. COVID-19 among Black people in Canada: a scoping review.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Apolipoprotein E and viral infection: Risks and Mechanisms.Molecular therapy. Nucleic acids · 2023
    Review
  18. Article
  19. Article
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Laurens HolmesNemours Children's Healthcare System, Wilmington, DE 19803, USA.
Michael EnwereNemours Children's Healthcare System, Wilmington, DE 19803, USA.
Janille WilliamsNemours Children's Healthcare System, Wilmington, DE 19803, USA.
Benjamin OgundeleNemours Children's Healthcare System, Wilmington, DE 19803, USA.
Prachi ChavanNemours Children's Healthcare System, Wilmington, DE 19803, USA.ORCID 0000-0003-4022-6605
Tatiana PiccoliNemours Children's Healthcare System, Wilmington, DE 19803, USA.
Chinaka ChinacheremNemours Children's Healthcare System, Wilmington, DE 19803, USA.
Camillia ComeauxNemours Children's Healthcare System, Wilmington, DE 19803, USA.
Lavisha PelaezNemours Children's Healthcare System, Wilmington, DE 19803, USA.ORCID 0000-0003-4509-8091
Osatohamwen OkundayeNemours Children's Healthcare System, Wilmington, DE 19803, USA.
Leslie StalnakerNemours Children's Healthcare System, Wilmington, DE 19803, USA.
Fanta KalleNemours Children's Healthcare System, Wilmington, DE 19803, USA.
Keeti DeepikaNemours Children's Healthcare System, Wilmington, DE 19803, USA.
Glen PhilipcienEmergency Department, Victoria Hospital, Castries, St. Lucia.
Maura PoleonSchool of Nursing, Florida International University, Miami, FL 33139, USA.ORCID 0000-0002-5482-0309
Gbadebo OgungbadeGlobal Health Services Initiatives Incorporated, Arlington, TX 76014 USA.ORCID 0000-0001-9596-4301
Hikma ElmiNemours Children's Healthcare System, Wilmington, DE 19803, USA.
Valescia JohnNemours Children's Healthcare System, Wilmington, DE 19803, USA.
Kirk W DabneyNemours Children's Healthcare System, Wilmington, DE 19803, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSocial and health inequities predispose vulnerable populations to adverse morbidity and mortality outcomes of epidemics and pandemics. While racial disparities in cumulative incidence (CmI) and mortality from the influenza pandemics of 1918 and 2009 implicated Blacks with survival disadvantage relative to Whites in the United States, COVID-19 currently indicates comparable disparities. We aimed to: (a) assess COVID-19 CmI by race, (b) determine the Black-White case fatality (CF) and risk differentials, and (c) apply explanatory model for mortality risk differentials.

methodsCOVID-19 data on confirmed cases and deaths by selective states health departments were assessed using a cross-sectional ecologic design. Chi-square was used for CF independence, while binomial regression model for the Black-White risk differentials.

resultsThe COVID-19 mortality CmI indicated Blacks/AA with 34% of the total mortality in the United States, albeit their 13% population size. The COVID-19 CF was higher among Blacks/AA relative to Whites; Maryland, (2.7% vs. 2.5%), Wisconsin (7.4% vs. 4.8%), Illinois (4.8% vs. 4.2%), Chicago (5.9% vs. 3.2%), Detroit (Michigan), 7.2% and St. John the Baptist Parish (Louisiana), 7.9%. Blacks/AA compared to Whites in Michigan were 15% more likely to die, CmI risk ratio (CmIRR) = 1.15, 95% CI, 1.01-1.32. Blacks/AA relative to Whites in Illinois were 13% more likely to die, CmIRR = 1.13, 95% CI, 0.93-1.39, while Blacks/AA compared to Whites in Wisconsin were 51% more likely to die, CmIRR = 1.51, 95% CI, 1.10-2.10. In Chicago, Blacks/AA were more than twice as likely to die, CmIRR = 2.24, 95% CI, 1.36-3.88.

conclusionSubstantial racial/ethnic disparities are observed in COVID-19 CF and mortality with Blacks/AA disproportionately affected across the United States.

Indexed as

BetacoronavirusBlack or African AmericanCoronavirus InfectionsCOVID-19Cross-Sectional StudiesFemaleHumansIncidenceMaleOdds RatioPandemicsPneumonia, ViralRegression AnalysisSARS-CoV-2United StatesWhite Peoplecase fatalityCOVID-19 (SARS-COV2)health disparitiesmortalityrace/ethnicityUnited States

Identifiers

PMID32560363
PMCPMC7345143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.