Evidence map›Paper›PMID 32560336›Full record

ArticleSensors (Basel, Switzerland)2020

Fusion iENA Scholar Study: Sensor-Navigated I-124-PET/US Fusion Imaging versus Conventional Diagnostics for Retrospective Functional Assessment of Thyroid Nodules by Medical Students.

Martin Freesmeyer, Thomas Winkens, Luis Weissenrieder, Christian Kühnel, Falk Gühne, Simone Schenke, Robert Drescher, Philipp Seifert

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Martin FreesmeyerClinic of Nuclear Medicine, Jena University Hospital, D-07749 Jena, Germany.
Thomas WinkensClinic of Nuclear Medicine, Jena University Hospital, D-07749 Jena, Germany.ORCID 0000-0002-8958-4801
Luis WeissenriederClinic of Nuclear Medicine, Jena University Hospital, D-07749 Jena, Germany.
Christian KühnelClinic of Nuclear Medicine, Jena University Hospital, D-07749 Jena, Germany.ORCID 0000-0003-3307-1772
Falk GühneClinic of Nuclear Medicine, Jena University Hospital, D-07749 Jena, Germany.
Simone SchenkeDivision of Nuclear Medicine, Department of Radiology and Nuclear Medicine, Magdeburg University Hospital, D-39120 Magdeburg, Germany.
Robert DrescherClinic of Nuclear Medicine, Jena University Hospital, D-07749 Jena, Germany.
Philipp SeifertClinic of Nuclear Medicine, Jena University Hospital, D-07749 Jena, Germany.ORCID 0000-0002-3447-4971
Jena University Hospital · DEUniversity Hospital Magdeburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In conventional thyroid diagnostics, the topographical correlation between thyroid nodules (TN) depicted on ultrasound (US) in axial or sagittal orientation and coronally displayed scintigraphy images can be challenging. Sensor-navigated I-124-PET/US fusion imaging has been introduced as a problem-solving tool for ambiguous cases. The purpose of this study was to investigate the results of multiple unexperienced medical students (MS) versus multiple nuclear medicine physicians (MD) regarding the overvalue of I-124-PET/US in comparison to conventional diagnostics (CD) for the functional assessment of TN.

methodsOut of clinical routine, cases with ambiguous findings on CD were selected for I-124-PET/US fusion imaging. Sixty-eight digital patient case files (PCF) of 34 patients (CDonly and CD+PET/US PCF) comprising 66 TN were provided to be retrospectively evaluated by 70 MD and 70 MS, respectively. A total of 2174 ratings (32.9 per TN) were carried out: 555 ratings (8.4 per TN) for CDonly and 532 ratings (8.1 per TN) for CD+PET/US by each MD and MS.

resultsFunctional assessment revealed 8.5%/11.7% (n.s.) (16.4%/25.8% (

conclusionThe additional application of sensor-navigated I-124-PET/US fusion imaging significantly influenced the functional assessment of TN positively, especially for unexperienced observers.

Indexed as

Positron-Emission TomographyStudents, MedicalThyroid NoduleUltrasonographyHumansIodine RadioisotopesRetrospective StudiesIodine-124Iodine Radioisotopesiodine-124medical studentsmultimodal imagingpositron emission tomographysensor-navigated fusion imagingthyroid nodulesultrasound

Identifiers

PMID32560336
PMCPMC7349481
OpenAlexW3036216193

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.