Evidence map›Paper›PMID 32560289›Full record

ArticlePharmaceutics2020

Comparison between Colistin Sulfate Dry Powder and Solution for Pulmonary Delivery.

Frédéric Tewes, Julien Brillault, Nicolas Gregoire, Jean-Christophe Olivier, Isabelle Lamarche, Christophe Adier, Anne-Marie Healy, Sandrine Marchand

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Therapeutic Interventions forJournal of clinical medicine · 2024
    Review
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Frédéric TewesINSERM U1070 "Pharmacology of anti-infective agents", 1 rue Georges Bonnet, Pôle Biologie Santé, 86022 Poitiers Cedex, France.ORCID 0000-0002-7865-718X
Julien BrillaultINSERM U1070 "Pharmacology of anti-infective agents", 1 rue Georges Bonnet, Pôle Biologie Santé, 86022 Poitiers Cedex, France.ORCID 0000-0003-4207-5089
Nicolas GregoireINSERM U1070 "Pharmacology of anti-infective agents", 1 rue Georges Bonnet, Pôle Biologie Santé, 86022 Poitiers Cedex, France.
Jean-Christophe OlivierUFR Médecine-Pharmacie Université de Poitiers, 6 rue de la milétrie, TSA 51115, 86073 Poitiers Cedex 9, France.
Isabelle LamarcheINSERM U1070 "Pharmacology of anti-infective agents", 1 rue Georges Bonnet, Pôle Biologie Santé, 86022 Poitiers Cedex, France.
Christophe AdierINSERM U1070 "Pharmacology of anti-infective agents", 1 rue Georges Bonnet, Pôle Biologie Santé, 86022 Poitiers Cedex, France.
Anne-Marie HealySSPC, The Science Foundation Ireland Research Centre for Pharmaceuticals, School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Panoz Institute, D02 PN40 Dublin 2, Ireland.ORCID 0000-0001-5093-9786
Sandrine MarchandINSERM U1070 "Pharmacology of anti-infective agents", 1 rue Georges Bonnet, Pôle Biologie Santé, 86022 Poitiers Cedex, France.
Inserm · FRScience Foundation Ireland · IEUniversité de Poitiers · FR

Funding

Science Foundation Ireland (SFI) 12/RC/2275, 12/RC/2275_P2 and SFI/12/RC2278)
6 · The paper itself

Abstract

To assess the difference in the fate of the antibiotic colistin (COLI) after its pulmonary delivery as a powder or a solution, we developed a COLI powder and evaluated the COLI pharmacokinetic properties in rats after pulmonary administration of the powder or the solution. The amorphous COLI powder prepared by spray drying was characterized by a mass median aerodynamic diameter and fine particle fraction of 2.68 ± 0.07 µm and 59.5 ± 5.4%, respectively, when emitted from a Handihaler

Indexed as

Calu-3 permeabilitycolistin dry powder inhalationnebulizationpharmacokinetics modelingpulmonary infections

Identifiers

PMID32560289
PMCPMC7356940
OpenAlexW3035177782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.