Evidence map›Paper›PMID 32560243›Full record

ArticleCancers2020

Viral and Immunological Analytes are Poor Predictors of the Clinical Treatment Response in Kaposi's Sarcoma Patients.

Salum J Lidenge, For Yue Tso, Yasaman Mortazavi, John R Ngowi, Danielle M Shea, Julius Mwaiselage, Charles Wood, John T West

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Is Kaposi sarcoma a novel comorbidity of cutaneous lymphoma? A systematic review of the literature.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Salum J LidengeNebraska Center for Virology, Lincoln, NE 68583, USA.
For Yue TsoNebraska Center for Virology, Lincoln, NE 68583, USA.
Yasaman MortazaviNebraska Center for Virology, Lincoln, NE 68583, USA.
John R NgowiDepartment of Academics and Research, Ocean Road Cancer Institute, Dar es Salaam P. O. Box 3592, Tanzania.
Danielle M SheaNebraska Center for Virology, Lincoln, NE 68583, USA.
Julius MwaiselageDepartment of Academics and Research, Ocean Road Cancer Institute, Dar es Salaam P. O. Box 3592, Tanzania.
Charles WoodNebraska Center for Virology, Lincoln, NE 68583, USA.ORCID 0000-0002-4256-1530
John T WestNebraska Center for Virology, Lincoln, NE 68583, USA.
University of Nebraska–Lincoln · USMuhimbili University of Health and Allied Sciences · TZOcean Road Cancer Institute · TZ

Funding

Seroprevalence of COVID-19 of cancer patients in TanzaniaU54CA190155 · NCI · UNIVERSITY OF NEBRASKA LINCOLN · PI SOLIMAN, AMR, WOOD, CHARLES · 2014 to 2022
$4.5M
Nebraska Center for VirologyP30GM103509 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 2012 to 2014
$3.3M
"Plasma and cellular immune biomarkers of Kaposi's sarcoma in HIV-1 suppressed patients"K43TW011418 · FIC · MUHIMBILI UNIVERSITY/ ALLIED HLTH SCIS · PI LIDENGE, SALUM JUMA · 2019 to 2023
$741k
FIC NIH HHS K43 TW011418NIH HHS K43TW011418NIH HHS P30 GM103509NIH HHS U54 CA190155
6 · The paper itself

Abstract

Kaposi's sarcoma-associated herpes virus (KSHV) is the etiologic agent for Kaposi's sarcoma (KS). The prognostic utility of KSHV and HIV-1 (human immunodeficiency virus) viremia as well as immunological parameters in clinical management of participants with KS is unclear. The objective of this study was to investigate viral and immunological parameters as predictors of KS treatment responses in participants with KS from sub-Saharan Africa (SSA). Plasma KSHV-DNA, HIV-1 viral load, total anti-KSHV antibody, KSHV-neutralizing antibody (nAb), cytokine/chemokine levels, and T-cell differentiation subsets were quantified before and after KS treatment in 13 participants with KS and in 13 KSHV-infected asymptomatic control individuals. One-way analysis of variance and the Mann-Whitney t-test were used to assess differences between groups where

Indexed as

cytokineHIV-1immune responsesKaposi’s sarcomaKSHVneutralizing antibodysub-Saharan AfricaT-cellstreatment response

Identifiers

PMID32560243
PMCPMC7352224
OpenAlexW3035349876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.