Evidence map›Paper›PMID 32560201›Full record

ArticleMolecules (Basel, Switzerland)2020

Efficacy, Stability, and Safety Evaluation of New Polyphenolic Xanthones Towards Identification of Bioactive Compounds to Fight Skin Photoaging.

Diana I S P Resende, Mariana C Almeida, Bruna Maciel, Helena Carmo, José Sousa Lobo, Carlotta Dal Pozzo, Sara M Cravo, Gonçalo P Rosa, Aida Kane-Pagès, Maria do Carmo Barreto and 3 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Heterocyclic Compounds as Synthetic Tyrosinase Inhibitors: Recent Advances.International journal of molecular sciences · 2023
    Review
  6. Article
  7. UV Filters: Challenges and Prospects.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  8. Natural and Artificial Photoprotective Agents.Molecules (Basel, Switzerland) · 2021
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Diana I S P ResendeLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, 4050-313 Porto, Portugal.ORCID 0000-0002-4077-6060
Mariana C AlmeidaLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, 4050-313 Porto, Portugal.
Bruna MacielLaboratório de Tecnologia Farmacêutica, Departamento do Medicamento, Faculdade de Farmácia, Universidade do Porto, 4050-313 Porto, Portugal.
Helena CarmoUCIBIO, REQUIMTE, Laboratório de Toxicologia, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, 4050-313 Porto, Portugal.ORCID 0000-0002-6650-5285
José Sousa LoboUCIBIO/REQUIMTE, MedTec-Laboratório de Tecnologia Farmacêutica, Departamento de Ciências do Medicamento, Faculdade de Farmácia, Universidade do Porto, 4050-313 Porto, Portugal.
Carlotta Dal PozzoUniversity of Ferrara, Dept. of Life Sciences and Biotechnology, Via Fossato di Mortara 17/1944121 Ferrara, Italy.
Sara M CravoLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, 4050-313 Porto, Portugal.ORCID 0000-0001-9314-8669
Gonçalo P RosacE3c-Centre for Ecology, Evolution and Environmental Changes / Azorean Biodiversity Group, 9500-321 Ponta Delgada, Portugal.ORCID 0000-0002-0706-8505
Aida Kane-PagèsFaculdade de Ciências e Tecnologia, Universidade dos Açores, 9500-321 Ponta Delgada, Portugal.
Maria do Carmo BarretocE3c-Centre for Ecology, Evolution and Environmental Changes / Azorean Biodiversity Group, 9500-321 Ponta Delgada, Portugal.ORCID 0000-0001-5797-8913
Isabel F AlmeidaUCIBIO/REQUIMTE, MedTec-Laboratório de Tecnologia Farmacêutica, Departamento de Ciências do Medicamento, Faculdade de Farmácia, Universidade do Porto, 4050-313 Porto, Portugal.ORCID 0000-0002-1498-048X
Maria Emília de SousaLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, 4050-313 Porto, Portugal.ORCID 0000-0002-5397-4672
Madalena M M PintoLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, 4050-313 Porto, Portugal.ORCID 0000-0002-4676-1409
Universidade do Porto · PTUniversidade dos Açores · PTUniversity of Ferrara · IT

Funding

Fundação para a Ciência e a Tecnologia PTDC/SAU-PUB/28736/2017 , UIDB/04423/2020 and UIDP/04423/2020
6 · The paper itself

Abstract

Antioxidants have long been used in the cosmetic industry to prevent skin photoaging, which is mediated by oxidative stress, making the search for new antioxidant compounds highly desirable in this field. Naturally occurring xanthones are polyphenolic compounds that can be found in microorganisms, fungi, lichens, and some higher plants. This class of polyphenols has a privileged scaffold that grants them several biological activities. We have previously identified simple oxygenated xanthones as promising antioxidants and disclosed as hit, 1,2-dihydroxyxanthone (

Indexed as

AntioxidantsSunscreening AgentsXanthonesDrug Evaluation, PreclinicalHumansKeratinocytesSkinSkin AgingUltraviolet RaysAntioxidantsSunscreening AgentsXanthones1,2-dihydroxyxanthoneantioxidantscollagenaseDPPHelastasephotoagingphototoxicityskintyrosinasexanthones

Identifiers

PMID32560201
PMCPMC7356587
OpenAlexW3034190025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.