Evidence map›Paper›PMID 32560198›Full record

ArticleBrain sciences2020

Early Motor Development Predicts Clinical Outcomes of Siblings at High-Risk for Autism: Insight from an Innovative Motion-Tracking Technology.

Angela Caruso, Letizia Gila, Francesca Fulceri, Tommaso Salvitti, Martina Micai, Walter Baccinelli, Maria Bulgheroni, Maria Luisa Scattoni

Registry-linked trialAbstract read
In one paragraph

Article in Brain sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06915805 (BABY@NET), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06915805 recruitingnot on this mapstarted 2023, after this paper: background citation

BABY@NET: A Technology-based National Surveillance Network for the Early Identification of Autism Spectrum Disorder and Other Neurodevelopmental Disorders in At-risk Populations

TypeobservationalSponsorIstituto Superiore di SanitàRan2023 to 2025Enrolled296ConditionsAutism Spectrum Disorder (ASD), Neurodevelopmental Disorders
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  20. Early Motor Signs in Autism Spectrum Disorder.Children (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Angela CarusoResearch Coordination and Support Service, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Roma, Italy.
Letizia GilaResearch Coordination and Support Service, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Roma, Italy.
Francesca FulceriResearch Coordination and Support Service, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Roma, Italy.
Tommaso SalvittiResearch Coordination and Support Service, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Roma, Italy.
Martina MicaiResearch Coordination and Support Service, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Roma, Italy.
Walter BaccinelliAb.Acus srl, Milano, via F. Caracciolo 77, 20155 Milano, Italy.ORCID 0000-0001-8888-4792
Maria BulgheroniAb.Acus srl, Milano, via F. Caracciolo 77, 20155 Milano, Italy.ORCID 0000-0001-8484-9834
Maria Luisa ScattoniResearch Coordination and Support Service, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Roma, Italy.ORCID 0000-0002-6659-0280

Funding

Italian Ministry of Health Network Project 'Italian Autism Spectrum Disorders Network: filling the gaps in the National Health System Care' NET 2013- 02355263MSCA-ITN-2018 - European Training Networks under Grant agreement (SAPIENS) "Shaping the social brain through early interactions" ID: 814302
6 · The paper itself

Abstract

Atypical motor patterns are potential early markers and predictors of later diagnosis of Autism Spectrum Disorder (ASD). This study aimed to investigate the early motor trajectories of infants at high-risk (HR) of ASD through MOVIDEA, a semi-automatic software developed to analyze 2D and 3D videos and provide objective kinematic features of their movements. MOVIDEA was developed within the Italian Network for early detection of Autism Spectrum Disorder (NIDA Network), which is currently coordinating the most extensive surveillance program for infants at risk for neurodevelopmental disorders (NDDs). MOVIDEA was applied to video recordings of 53 low-risk (LR; siblings of typically developing children) and 50 HR infants' spontaneous movements collected at 10 days and 6, 12, 18, and 24 weeks. Participants were grouped based on their clinical outcome (18 HR received an NDD diagnosis, 32 HR and 53 LR were typically developing). Results revealed that early developmental trajectories of specific motor parameters were different in HR infants later diagnosed with NDDs from those of infants developing typically. Since MOVIDEA was useful in the association of quantitative measures with specific early motor patterns, it should be applied to the early detection of ASD/NDD markers.

Indexed as

autism spectrum disorderhigh-risk infantsmotor developmentneurodevelopmental disordersscreeningtechnology

Identifiers

PMID32560198
PMCPMC7349903

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.