ReviewMedicines (Basel, Switzerland)2020
Oral Manifestations of Inflammatory Bowel Disease and the Role of Non-Invasive Surrogate Markers of Disease Activity.
Review in Medicines (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Patients with inflammatory bowel disease have a higher chance of developing periodontitis: A systematic review and meta-analysis.Frontiers in medicine · 2022Pooled it
- Dermatological Manifestations in Pediatric Inflammatory Bowel Disease.Medicina (Kaunas, Lithuania) · 2020Pooled it
- The Knowledge, Attitude, and Perception (KAP) of Healthcare Professionals in Pediatric Settings Toward Oral Manifestations of Inflammatory Bowel Disease (IBD): A Survey-Based Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Bilateral Lower Lip Swelling as an Early Manifestation of Crohn's Disease in a 16-Year-Old Patient: A Case Report.Case reports in dentistry · 2026Article
- Oral and upper gastrointestinal Crohn's disease: new perspectives on pathogenesis and clinical management.Frontiers in cell and developmental biology · 2026Review
- Patient with Inflammatory Bowel Disease in a Dental Office-Which Antibiotic to Choose?-Narrative Review.Journal of clinical medicine · 2025Review
- Interpretable machine learning applied to high-dimensional salivary proteomics accurately classifies pediatric inflammatory bowel diseases.medRxiv : the preprint server for health sciences · 2025Article
- Oral Microbial Diversity is Associated with Biologic Treatment and Metabolic Health Status but not with Disease Activity in Patients with Inflammatory Bowel Disease.Crohn's & colitis 360 · 2025Article
- Salivary Calprotectin as a Biomarker in Early Onset Inflammatory Bowel Disease: A Pilot Study.Journal of clinical medicine · 2025Article
- Oral Extraintestinal Manifestations of Inflammatory Bowel Disease: The Temporal Relationship Between Oral and Intestinal Symptoms.Crohn's & colitis 360 · 2025Article
- Oral mucosal findings in ambulatory patients with inflammatory bowel disease.Brazilian oral research · 2025Article
- Orofacial Granulomatosis and Crohn's Disease: A Case Series.ACG case reports journal · 2024Article
- Association of oral manifestations with severity of the disease in ulcerative colitis patients.BMC gastroenterology · 2024Article
- Oral Anti-Inflammatory and Symbiotic Effects of Fermented Lingonberry Juice-Potential Benefits in IBD.Nutrients · 2024Review
- Specific Oral Manifestations in Adults with Crohn's Disease.Journal of clinical medicine · 2024Article
- Predicting diagnostic biomarkers associated with immune infiltration in Crohn's disease based on machine learning and bioinformatics.European journal of medical research · 2023Article
- Potential Oral Microbial Markers for Differential Diagnosis of Crohn's Disease and Ulcerative Colitis Using Machine Learning Models.Microorganisms · 2023Article
- Rare Oral Crohn's Disease: A Case Report.Cureus · 2023Article
- Oral manifestations associated with inflammatory bowel disease and early endoscopic findings in patients with spondyloarthritis.BMC oral health · 2022Article
- Polyphenols and Ulcerative Colitis: An Exploratory Study of the Effects of Red Wine Consumption on Gut and Oral Microbiome in Active-Phase Patients.Molecular nutrition & food research · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis (UC), can be associated with several extra-intestinal manifestations requiring a multidisciplinary management both in terms of work-up and therapy. Oral lesions are common in patients with IBD, with a prevalence ranging from 5% to 50%. These can represent an oral location of IBD as well as a side-effect of drugs used to treat the intestinal disease. Oral manifestations, occurring in patients with IBD, can be divided in nonmalignant, specific, and non-specific ones, and malignant lesions. While there is undoubtedly a need to search for an IBD in patients with oral lesions associated with intestinal symptoms, the work-up of those with an exclusive oral lesion should be personalized. Fecal calprotectin is a non-invasive marker of intestinal inflammation and may be used to select which patients need to undergo endoscopic examination, thereby avoiding unnecessary investigations. The pharmacological armamentarium to treat oral lesions associated with IBD includes topical or systemic corticosteroids, immunosuppressive agents, and biologic drugs.
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