Evidence map›Paper›PMID 32560107›Full record

ArticlePharmaceutics2020

Shear Stress-Dependent Targeting Efficiency Using Self-Assembled Gelatin-Oleic Nanoparticles in a Biomimetic Microfluidic System.

Taehee Kang, Chulhun Park, Nileshkumar Meghani, Thao T D Tran, Phuong H L Tran, Beom-Jin Lee

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Taehee KangCollege of Pharmacy, Ajou University, Suwon 16499, Korea.
Chulhun ParkCollege of Pharmacy, Ajou University, Suwon 16499, Korea.ORCID 0000-0003-4951-3213
Nileshkumar MeghaniCollege of Pharmacy, Ajou University, Suwon 16499, Korea.
Thao T D TranDepartment for Management of Science and Technology Development, Ton Duc Thang University, Ho Chi Minh City, Vietnam.
Phuong H L TranSchool of Medicine, Deakin University, Geelong 3217, Australia.
Beom-Jin LeeCollege of Pharmacy, Ajou University, Suwon 16499, Korea.ORCID 0000-0003-0922-3289
Ajou University · KRDeakin University · AUTon Duc Thang University · VNUniversity of Alberta · CA

Funding

Ministry of Science and ICT 2020R1A2C2008307
6 · The paper itself

Abstract

Cellular properties and microenvironments, as well as the characteristics of nanoparticles (NPs), affect the cellular uptake and cytotoxic effects of drug-loaded NPs. Since there is fluid flow in the human blood system, fluid flow also affects the drug delivery efficiency of NPs. This study aimed to evaluate the cellular behaviors of drug-loaded soft NPs on A549 cancer cells under different levels of shear stress (0.5, 5, and 50 dynes/cm

Indexed as

biomimetic shear stresscell dynamic environmentcellular uptakecoumarin-6fattigation-platform NPsgelatin–oleic conjugateinhibitory concentrationpaclitaxelself-assembly

Identifiers

PMID32560107
PMCPMC7356760
OpenAlexW3035015021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.