ArticleDiagnostics (Basel, Switzerland)2020
Mobile Laboratory Reveals the Circulation of Dengue Virus Serotype I of Asian Origin in Medina Gounass (Guediawaye), Senegal.
Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Diagnostic accuracy of recombinase polymerase amplification-based assays for mosquito-borne virus detection in clinical samples: a systematic review and meta-analysis.Frontiers in cellular and infection microbiology · 2026Pooled it
- Analysis of dengue fever disease in West Africa.Experimental biology and medicine (Maywood, N.J.) · 2023Pooled it
- Epidemiology of yellow fever virus in humans, arthropods, and non-human primates in sub-Saharan Africa: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2022Pooled it
- Dengue Virus Infection and Associated Risk Factors in Africa: A Systematic Review and Meta-Analysis.Viruses · 2021Pooled it
- A decade of dengue disease burden in Africa (2013-2023): a systematic review.Travel medicine and infectious diseasePooled it
- Rapid On-Site Detection of Arboviruses by a Direct RT-qPCR Assay.Biosensors · 2023Article
- Study on bioaerosol diffusion and deposition in a mobile BSL-4 laboratory based on air age analysis.Journal of building engineering · 2023Article
- African countries from the Pasteur Network reexamine their syndromic sentinel surveillance system associated with household contact within the AFROSCREEN program.Frontiers in public health · 2023Article
- Recombinase Polymerase Amplification-Based Biosensors for Rapid Zoonoses Screening.International journal of nanomedicine · 2023Review
- Re-Emergence of Dengue Serotype 3 in the Context of a Large Religious Gathering Event in Touba, Senegal.International journal of environmental research and public health · 2022Article
- Analysis of a Dengue Virus Outbreak in Rosso, Senegal 2021.Tropical medicine and infectious disease · 2022Article
- Dengue vectors in Africa: A review.Heliyon · 2022Article
- Rapid molecular assays for the detection of the four dengue viruses in infected mosquitoes.Gates open research · 2022Article
- Tracing and tracking the emergence, epidemiology and dispersal of dengue virus to Africa during the 20th century.One health (Amsterdam, Netherlands) · 2021Article
- Epidemiology and Laboratory Diagnostics of Dengue, Yellow Fever, Zika, and Chikungunya Virus Infections in Africa.Pathogens (Basel, Switzerland) · 2021Review
- Emergence of dengue virus serotype 2 in Mauritania and molecular characterization of its circulation in West Africa.PLoS neglected tropical diseases · 2021Article
- Multifoci and multiserotypes circulation of dengue virus in Senegal between 2017 and 2018.BMC infectious diseases · 2021Article
- Genomic investigation of a dengue virus outbreak in Thiès, Senegal, in 2018.Scientific reports · 2021Observational
- Article
- Field Deployment of a Mobile Biosafety Laboratory Reveals the Co-Circulation of Dengue Viruses Serotype 1 and Serotype 2 in Louga City, Senegal, 2017.Journal of tropical medicine · 2021Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 3 countries.
Funding
Abstract
With the growing success of controlling malaria in Sub-Saharan Africa, the incidence of fever due to malaria is in decline, whereas the proportion of patients with non-malaria febrile illness (NMFI) is increasing. Clinical diagnosis of NMFI is hampered by unspecific symptoms, but early diagnosis is a key factor for both better patient care and disease control. The aim of this study was to determine the arboviral aetiologies of NMFI in low resource settings, using a mobile laboratory based on recombinase polymerase amplification (RPA) assays. The panel of tests for this study was expanded to five arboviruses: dengue virus (DENV), zika virus (ZIKV), yellow fever virus (YFV), chikungunya virus (CHIKV), and rift valley fever virus (RVFV). One hundred and four children aged between one month and 115 months were enrolled and screened. Three of the 104 blood samples of children <10 years presented at an outpatient clinic tested positive for DENV. The results were confirmed by RT-PCR, partial sequencing, and non-structural protein 1 (NS1) antigen capture by ELISA (Biorad, France). Phylogenetic analysis of the derived DENV-1 sequences clustered them with sequences of DENV-1 isolated from Guangzhou, China, in 2014. In conclusion, this mobile setup proved reliable for the rapid identification of the causative agent of NMFI, with results consistent with those obtained in the reference laboratory's settings.
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