Evidence map›Paper›PMID 32559122›Full record

ArticleAutophagy2021

Neutrophils use selective autophagy receptor Sqstm1/p62 to target

Josie F Gibson, Tomasz K Prajsnar, Christopher J Hill, Amy K Tooke, Justyna J Serba, Rebecca D Tonge, Simon J Foster, Andrew J Grierson, Philip W Ingham, Stephen A Renshaw and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Autophagy · 2025
    Article
  3. Article
  4. Zebrafish (International journal of molecular sciences · 2024
    Review
  5. Complement C3 deposition restricts the proliferation of internalizedFrontiers in cellular and infection microbiology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Eliminating the invading extracellular and intracellular FnBpFrontiers in cellular and infection microbiology · 2023
    Article
  11. Article
  12. Article
  13. LC3-Associated Phagocytosis in Bacterial Infection.Pathogens (Basel, Switzerland) · 2022
    Review
  14. Article
  15. Antigen Presentation and Autophagy in Teleost Adaptive Immunity.International journal of molecular sciences · 2022
    Review
  16. Review
  17. Zebrafish: An Attractive Model to StudyPharmaceuticals (Basel, Switzerland) · 2021
    Review
  18. Article
  19. Autophagy inFrontiers in cellular and infection microbiology · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Josie F GibsonDepartment of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, UK.ORCID 0000-0002-4299-2488
Tomasz K PrajsnarDepartment of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, UK.ORCID 0000-0001-6562-8630
Christopher J HillDepartment of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK.
Amy K TookeDepartment of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK.ORCID 0000-0002-8719-5263
Justyna J SerbaDepartment of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, UK.
Rebecca D TongeSheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, Sheffield, UK.
Simon J FosterFlorey Institute, University of Sheffield, Sheffield, UK.
Andrew J GriersonThe Bateson Centre, University of Sheffield, Sheffield, UK.
Philip W InghamInstitute of Molecular and Cell Biology, Agency of Science, Technology and Research (A-star), Singapore.ORCID 0000-0001-8224-9958
Stephen A RenshawDepartment of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, UK.
Simon A JohnstonDepartment of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, UK.ORCID 0000-0002-3429-9536
University of Sheffield · GBAgency for Science, Technology and Research · SGLeiden University · NL

Funding

Medical Research Council G0700091Medical Research Council MR/J009156/1Medical Research Council MR/M004864/1Medical Research Council MR/N02995X/1Medical Research Council MR/R001111/1
6 · The paper itself

Abstract

Macroautophagy/autophagy functions to degrade cellular components and intracellular pathogens. Autophagy receptors, including SQSTM1/p62, target intracellular pathogens.

Indexed as

AnimalsAnimals, Genetically ModifiedAutophagyMacrophagesMicrotubule-Associated ProteinsNeutrophilsPhagosomesSequestosome-1 ProteinStaphylococcus aureusZebrafishZebrafish ProteinsMicrotubule-Associated ProteinsSequestosome-1 ProteinZebrafish ProteinsAutophagybacterial infectionhost-pathogen interactionsneutrophilsqstm1/p62staphylococcus aureusxenophagyzebrafish

Identifiers

PMID32559122
PMCPMC8204994
OpenAlexW3036437775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.