ArticleDiagnostic and interventional radiology (Ankara, Turkey)2020
Percutaneous endobiliary forceps biopsy of biliary strictures for histopathologic examination.
Article in Diagnostic and interventional radiology (Ankara, Turkey), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Systematic review and meta-analysis of percutaneous transluminal forceps biopsy for diagnosing malignant biliary strictures.European radiology · 2022Pooled it
- Assessing the Feasibility and Diagnostic Value of Percutaneous Transhepatic Cholangioscopy Biopsy for Biliary Strictures.Cardiovascular and interventional radiology · 2025Article
- False-negative factors of percutaneous transluminal clamp biopsy for suspected malignant biliary stricture: 194 cases analyzed from a single center.Insights into imaging · 2024Article
- An alternative method in the diagnosis of intrabiliary lesions: Percutaneous endobiliary brush biopsy.Hepatology forum · 2024Article
- Novel method to biopsy aneurysmal bone cysts in children.Skeletal radiology · 2023Article
- Percutaneous transhepatic intraluminal forceps biopsy for patients with biliary stricture after endoscopic retrograde approach failure: a retrospective study.Quantitative imaging in medicine and surgery · 2023Article
- Percutaneous insertion of a novel dedicated metal stent to treat malignant hilar biliary obstruction.World journal of gastrointestinal oncology · 2022Article
- Endobiliary biopsy.World journal of gastrointestinal endoscopy · 2022Review
- Treatment of Malignant Bile Duct Obstruction: What the Interventional Radiologist Needs to Know.Seminars in interventional radiology · 2021Review
- Tissue sampling for biliary strictures using novel elbow biopsy forceps.Scientific reports · 2021Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe aimed to investigate the feasibility, accuracy and safety of percutaneous endobiliary cholangio-forceps biopsy of biliary strictures in our institution.
methodsA total of 13 percutaneous transhepatic endobiliary biopsies (7 men and 6 women, mean age 66.85±16.76 years) were performed between January 2015 and March 2019 using a transluminal forceps biopsy device. Technical success, rate of complications, number of biopsy specimens, procedure and fluoroscopy time, mean radiation exposure were evaluated; sensitivity and accuracy were calculated.
resultsTechnical success, i.e., acquisition of at least three (median, 3.00; range, 3-5) macroscopic representative samples, could be achieved in all 13 biopsies. Access was gained via the right liver lobe in 12 of 13 cases (92.3%). All patients presented blood work indicative of cholestasis prior the intervention, with mean bilirubin 4.72±3.72 µmol/L, mean γ-glutamyl transferase 574.16 ± 360.92 IU/L, and median alkaline phosphatase 407 IU/L (165-1366 IU/L). In 12 of 13 cases (92.3%), biopsied material was sufficient for the pathologist to make a histopathologic diagnosis. Analysis revealed cases of malignancy in eight of 13 cases (61.5%), all of which turned out to be cases of cholangiocarcinoma. In four benign cases (30.8%), diagnosis was considered to be confirmed by further imaging or clinical follow-ups, which showed no signs of progressive disease. There was one case (7.7%) of a false-negative result with proof of malignancy in subsequent surgical tissue extraction. A calculation of diagnostic performance yielded a sensitivity rate of 88.9% and an accuracy rate of 92.3%. There was one case of minor and one case of major complication in our study collective, leading to an overall complication rate of 15.4%.
conclusionPercutaneous transhepatic biliary drainage (PTBD)-based forceps biopsy via the transhepatic drainage tract in patients with biliary obstruction of unknown origin is a technically feasible and safe technique with good diagnostic value rates. The procedure should be considered in patients not suitable for endoscopic strategies with indication for establishment of PTBD.
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