ReviewExperimental biology and medicine (Maywood, N.J.)2020
Fast intrinsic optical signal correlates with activation phase of phototransduction in retinal photoreceptors.
Review in Experimental biology and medicine (Maywood, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 20 citations in OpenAlex.
- Spatio-temporal optical coherence imaging and tomography forJournal of biomedical optics · 2026Review
- Evaluating Human Rod Photoreceptor Function Using Pixelwise Intensity-Based Optoretinography.Translational vision science & technology · 2026Article
- ƒ(Cell): Software for Reproducible Analysis of Optoretinograms.Translational vision science & technology · 2026Article
- Functional OCT with parfocal retinal stimulation enables multi-site optoretinography under a single dark adaptation.Biomedical optics express · 2026Article
- Recent Developments in Photoreceptor Optoretinography and Progress Toward Clinical Use.Translational vision science & technology · 2025Review
- Ultrasound Flow Imaging Study on Rat Brain with Ultrasound and Light Stimulations.Bioengineering (Basel, Switzerland) · 2024Article
- Intrinsic signal optoretinography of dark adaptation abnormality due to rod photoreceptor degeneration.Experimental biology and medicine (Maywood, N.J.) · 2024Article
- Light-adapted flicker optoretinograms captured with a spatio-temporal optical coherence-tomography (STOC-T) system.Biomedical optics express · 2022Article
- Quantification of intrinsic optical signals in the outer human retina using optical coherence tomography.Annals of the New York Academy of Sciences · 2022Article
- Intrinsic signal optoretinography of dark adaptation kinetics.Scientific reports · 2022Article
- Functional Optical Coherence Tomography for Intrinsic Signal Optoretinography: Recent Developments and Deployment Challenges.Frontiers in medicine · 2022Review
- Challenges Associated With Ellipsoid Zone Intensity Measurements Using Optical Coherence Tomography.Translational vision science & technology · 2021Article
- Interpretation of anatomic correlates of outer retinal bands in optical coherence tomography.Experimental biology and medicine (Maywood, N.J.) · 2021Review
- OCT imaging of rod mitochondrial respirationExperimental biology and medicine (Maywood, N.J.) · 2021Review
- Toward a clinical optoretinogram: a review of noninvasive, optical tests of retinal neural function.Annals of translational medicine · 2021Review
- In vivo optoretinography of phototransduction activation and energy metabolism in retinal photoreceptors.Journal of biophotonics · 2021Article
- Functional optoretinography: concurrent OCT monitoring of intrinsic signal amplitude and phase dynamics in human photoreceptors.Biomedical optics express · 2021Article
- Functional intrinsic optical signal imaging for objective optoretinography of human photoreceptors.Experimental biology and medicine (Maywood, N.J.) · 2021Article
- Super-resolution ophthalmoscopy: Virtually structured detection for resolution improvement in retinal imaging.Experimental biology and medicine (Maywood, N.J.) · 2021Review
- Functional optical coherence tomography enablesBiomedical optics express · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
impact statementAs the center of phototransduction, retinal photoreceptors are responsible for capturing and converting photon energy to bioelectric signals for following visual information processing in the retina. This article summarizes experimental observation and discusses biophysical mechanism of fast photoreceptor-intrinsic optical signal (IOS) correlated with early phase of phototransduction. Quantitative imaging of fast photoreceptor-IOS may provide objective optoretinography to advance the study and diagnosis of age-related macular degeneration, retinitis pigmentosa, diabetic retinopathy, and other eye diseases that can cause photoreceptor dysfunctions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.