Evidence map›Paper›PMID 32558272›Full record

ArticleImmunity, inflammation and disease2020

Hematological reactions in the inhabitants of the Arctic on a polar night and a polar day.

Svetlana N Balashova, Anna V Samodova, Liliya K Dobrodeeva, Natalya K Belisheva

Open access · goldAbstract read
In one paragraph

Article in Immunity, inflammation and disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Svetlana N BalashovaN. Laverov Federal Center for Integrated Arctic Research, Arkhangelsk, Russia.ORCID 0000-0003-4828-6485
Anna V SamodovaN. Laverov Federal Center for Integrated Arctic Research, Arkhangelsk, Russia.ORCID 0000-0001-9835-8083
Liliya K DobrodeevaN. Laverov Federal Center for Integrated Arctic Research, Arkhangelsk, Russia.ORCID 0000-0001-5080-6502
Natalya K BelishevaResearch Centre for Human Adaptation in the Arctic, Branch of the Federal Research Centre "Kola Science Centre of the Russian Academy of Sciences", Apatity, Russia.ORCID 0000-0002-5504-2983
Northern (Arctic) Federal University · RUKola Science Centre · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study is to identify the features of hematological reactions in the inhabitants of the Arctic territory of the Kola Peninsula on a polar night and a polar day.

methodsThe study included determining the hemogram, neutrograms, monocytograms, lymphocytograms, and phagocytic activity neutrophil granulocytes, enzyme immunoassay, flow cytometry.

resultsIt was established that during the polar night, there is an increase in the activity of migration of leukocytes from the marginal pool to the circulating pool, an increase in the intensity of phagocytosis by neutrophils, an increase in the concentrations of noradrenaline, cortisol, as well as an increase in hyperergic reactions involving immunoglobulin E and inhibitory processes due to an increase in interleukin-10.

conclusionA prolonged lack of sunlight causes a decrease in the reserve capacity for regulating homeostasis and forces the body to use proliferative reactions, which is reflected in the increase in stab neutrophils, large lymphocytes in the structure of the lymphocytogram and CD10+ lymphocytes. In winters, the frequency of neutropenia registration also increases to 13% of cases, the deficit of phagocytic activity of neutrophils; lymphopenia is recorded in 20% with T-helper deficiency (37%). A part of the population probably has a relatively high degree of vulnerability to the action of natural environmental factors and is not able to completely restore the initial levels of the effectiveness of adaptation reactions in the summer. So at the end of the polar day in 8% of adults born in the north, neutropenia is recorded and in 21%-lymphopenia.

Indexed as

NeutrophilsAdultAgedArctic RegionsHumansLeukocyte CountMiddle AgedYoung AdultArcticcortisolcytokineslymphocytesmonocytesneutrophilsnoradrenalinephotoperiodreagins

Identifiers

PMID32558272
PMCPMC7416016
OpenAlexW3036821920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.