ArticleMagnetic resonance in medicine2020
Automated mitral valve vortex ring extraction from 4D-flow MRI.
Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 11 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Optimization of Non-contrast Enhanced 1.5 Tesla and 3 Tesla Cardiac Magnetic Resonance Imaging Techniques and Acquisition of Normal Values
Cardiac Blood Flow Patterns Associated With Regional and Global Left Ventricular Myocardial Damage: an Explorative Study by Cardiac Magnetic Resonance
Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Comprehensive CMR evaluation including 4D flow-derived E/A vorticity ratio in overweight adults with and without type 2 diabetes mellitus.Cardiovascular diabetology · 2025Trial
- Impact of Contour Boundary Offsets on 4D Flow CMR-Derived Intracardiac Haemodynamic Parameters.Journal of cardiovascular development and disease · 2026Article
- Automated 4D flow MRI pipeline for the quantification of advanced hemodynamic parameters in the left atrium.Scientific reports · 2026Article
- 4D flow MRI-based grading of left ventricular diastolic dysfunction: a validation study against echocardiography.European radiology · 2025Article
- Left ventricle diastolic vortex ring characterization in ischemic cardiomyopathy: insight into atrio-ventricular interplay.Medical & biological engineering & computing · 2024Article
- Article
- Diastolic flow in the left ventricular outflow tract - A normal physiological and underappreciated echocardiographic finding.Australasian journal of ultrasound in medicine · 2022Article
- Four-dimensional flow cardiac magnetic resonance assessment of left ventricular diastolic function.Frontiers in cardiovascular medicine · 2022Review
- Lagrangian-averaged vorticity deviation of spiraling blood flow in the heart during isovolumic contraction and ejection phases.Medical & biological engineering & computing · 2021Article
- A Hybrid Approach for Cardiac Blood Flow Vortex Ring Identification Based on Optical Flow and Lagrangian Averaged Vorticity Deviation.Frontiers in physiology · 2021Article
- Automated mitral valve vortex ring extraction from 4D-flow MRI.Magnetic resonance in medicine · 2020Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo present and validate a method for automated extraction and analysis of the temporal evolution of the mitral valve (MV) vortex ring from MR 4D-flow data.
methodsThe proposed algorithm uses the divergence-free part of the velocity vector field for Q criterion-based identification and tracking of MV vortex ring core and region within the left ventricle (LV). The 4D-flow data of 20 subjects (10 healthy controls, 10 patients with ischemic heart disease) were used to validate the algorithm against visual analysis as well as to assess the method's sensitivity to manual LV segmentation. Quantitative MV vortex ring parameters were analyzed with respect to both their differences between healthy subjects and patients and their correlation with transmitral peak velocities.
resultsThe algorithm successfully extracted MV vortex rings throughout the entire cardiac cycle, which agreed substantially with visual analysis (Cohen's kappa = 0.77). Furthermore, vortex cores and regions were robustly detected even if a static end-diastolic LV segmentation mask was applied to all frames (Dice coefficients 0.82 ± 0.08 and 0.94 ± 0.02 for core and region, respectively). Early diastolic MV vortex ring vorticity, kinetic energy and circularity index differed significantly between healthy controls and patients. In contrast to vortex shape parameters, vorticity and kinetic energy correlated strongly with transmitral peak velocities.
conclusionAn automated method for temporal MV vortex ring extraction demonstrating robustness with respect to LV segmentation strategies is introduced. Quantitative vortex parameter analysis indicates importance of the MV vortex ring for LV diastolic (dys)function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.