Evidence map›Paper›PMID 32557170›Full record

SynthesisPathology oncology research : POR2020

Involvement of Helicobacter Pylori in Ocular Adnexa Lymphoma.

Antonio Travaglino, Mirella Pace, Silvia Varricchio, Daniela Russo, Novella Pugliese, Alessandro Severino, Marco Picardi, Fabrizio Pane, Luigi Insabato, Stefania Staibano and 1 more

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Pathology oncology research : POR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Infectious etiologies of conjunctival tumors.Expert review of ophthalmology · 2025
    Article
  4. Correlation between diabetic retinopathy andInternational journal of ophthalmology · 2023
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Antonio TravaglinoDepartment of Advanced Biomedical Sciences, Pathology Section, Anatomic Pathology Unit, University of Naples "Federico II", Via Sergio Pansini, 5, 80131, Naples, Italy.
Mirella PaceDepartment of Advanced Biomedical Sciences, Pathology Section, Anatomic Pathology Unit, University of Naples "Federico II", Via Sergio Pansini, 5, 80131, Naples, Italy.
Silvia VarricchioDepartment of Advanced Biomedical Sciences, Pathology Section, Anatomic Pathology Unit, University of Naples "Federico II", Via Sergio Pansini, 5, 80131, Naples, Italy.
Daniela RussoDepartment of Advanced Biomedical Sciences, Pathology Section, Anatomic Pathology Unit, University of Naples "Federico II", Via Sergio Pansini, 5, 80131, Naples, Italy.
Novella PuglieseDepartment of Clinical Medicine and Surgery, Hematology Section, University of Naples "Federico II", Naples, Italy.
Alessandro SeverinoDepartment of Clinical Medicine and Surgery, Hematology Section, University of Naples "Federico II", Naples, Italy.
Marco PicardiDepartment of Clinical Medicine and Surgery, Hematology Section, University of Naples "Federico II", Naples, Italy.
Fabrizio PaneDepartment of Clinical Medicine and Surgery, Hematology Section, University of Naples "Federico II", Naples, Italy.
Luigi InsabatoDepartment of Advanced Biomedical Sciences, Pathology Section, Anatomic Pathology Unit, University of Naples "Federico II", Via Sergio Pansini, 5, 80131, Naples, Italy.
Stefania StaibanoDepartment of Advanced Biomedical Sciences, Pathology Section, Anatomic Pathology Unit, University of Naples "Federico II", Via Sergio Pansini, 5, 80131, Naples, Italy.
Massimo MascoloDepartment of Advanced Biomedical Sciences, Pathology Section, Anatomic Pathology Unit, University of Naples "Federico II", Via Sergio Pansini, 5, 80131, Naples, Italy. mmascol@gmail.com.ORCID http://orcid.org/0000-0002-2576-220X
University of Naples Federico II · ITFederico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori has been proposed as a possible etiologic factor of ocular adnexa lymphoma (OAL), although with conflicting results. To assess the involvement of H. pylori in OAL, as (1) H. pylori DNA positivity on OAL specimens, and (2) prevalence of H. pylori gastric infection in patients with OAL. A systematic review of studies assessing H. pylori in patients with OAL was conducted by searching electronic databases from their inception to May 2019. Pooled positivity for H. pylori in OAL specimens detected by polymerase chain reaction, and pooled prevalence of H. pylori gastric infection, were calculated with 95% confidence interval (CI). Eleven studies with 308 patients were included. Pooled positivity for H. pylori was 16.8% in all OALs and 22.7% in MALT OAL, with high heterogeneity among studies. Pooled prevalence of H. pylori gastric infection in patients with OAL was 34.7%, with low statistical heterogeneity. In conclusion, H. pylori seems to be involved in a subset of OAL, but the heterogeneity found needs to be investigated in further studies. The prevalence of H. pylori gastric infection in patients with OAL does not seem to differ from that of the general population.

Indexed as

Eye NeoplasmsHelicobacter InfectionsHelicobacter pyloriHumansLymphomaPrognosisAntibioticExtranodalHelicobacter pyloriLymphomaOcular adnexaOrbit

Identifiers

PMID32557170
OpenAlexW3036321517

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.