Evidence map›Paper›PMID 32557108›Full record

ArticleLa Radiologia medica2021

Study on brain structure network of patients with delayed encephalopathy after carbon monoxide poisoning: based on diffusion tensor imaging.

Wenqian Jiang, Ziru Zhao, Qingyu Wu, Liang Wang, Lu Zhou, Dan Li, Laichang He, Yongming Tan

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Article in La Radiologia medica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wenqian Jiang *Department of Radiology, The First Affiliated Hospital of Nanchang University, Yongwaizheng Street 17, Nanchang, 330006, Jiangxi Province, China.
Ziru Zhao *Department of Radiology, The First Affiliated Hospital of Nanchang University, Yongwaizheng Street 17, Nanchang, 330006, Jiangxi Province, China.
Qingyu WuDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Yongwaizheng Street 17, Nanchang, 330006, Jiangxi Province, China.
Liang WangRehabilitation Department, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Lu ZhouRehabilitation Department, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Dan LiDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Yongwaizheng Street 17, Nanchang, 330006, Jiangxi Province, China.
Laichang HeDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Yongwaizheng Street 17, Nanchang, 330006, Jiangxi Province, China.
Yongming TanDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Yongwaizheng Street 17, Nanchang, 330006, Jiangxi Province, China. tanyongming1209@163.com.ORCID http://orcid.org/0000-0002-0650-3763
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze the network alteration characteristics of brain structure network in patients with delayed encephalopathy after CO poisoning (DEACMP) based on diffusion tensor imaging (DTI), and to explore the structural correlation neuroimaging mechanism of DEACMP cognitive impairment.

methodsDTI scanning was performed in 33 patients with DEACMP and 25 healthy controls (HCs) who were matched in age and sex. The whole brain was divided into 90 regions by automated anatomical marker templates. The continuous tracing method was used to reconstruct the brain fiber bundle connection and construct the brain structure weighted network. The global and regional properties were computed by graph theoretical analysis. To compare the brain network regional properties between the DEACMP group and the HCs group, two-sample t test (false discovery rate correction, P < 0.05) was utilized. The correlations between the brain structural network properties and clinical parameters were further analyzed.

resultsBoth of the two groups were found to follow the efficient small-world characteristics. The shortest path length of the DEACMP group increased (L

conclusionBy comparing the differences and changes in the topological properties and nodes of the brain structure network between DEACMP group and HCs group, the degree of related brain regions, especially the damage of higher brain functions in DEACMP patients, was verified, which was helpful to understand the cognitive damage caused by CO poisoning and to predict the efficacy of late remodeling. Small-worldness is a dynamic reorganization of the small-world topology and its community structure from the brain network to provide system-wide flexibility and adaptability (Barbey in Trends Cogn Sci 22(1):8-20, 2018). The combination with DTI is helpful for the accurate localization of brain structural damage, especially in DEACMP patients.

Indexed as

Diffusion Tensor ImagingAdultAgedAlgorithmsBrain DiseasesCarbon Monoxide PoisoningCase-Control StudiesFemaleHumansImage Interpretation, Computer-AssistedMaleMiddle AgedNeurocognitive DisordersBrainDelayed encephalopathy after carbon monoxide poisoningDiffusion tensor imagingGraph theoryNetworkSmall-worldness

Identifiers

PMID32557108
OpenAlexW3036631845

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.